This study found that TLR2 and its ligand CEP are crucial for maintaining hair follicle health and stimulating hair growth, with deficiencies observed in aging and obesity potentially reducing regeneration.
April 2017 in “Journal of nutritional health & food engineering” This article discusses the widespread issue of vitamin D deficiency affecting over 65% of the UAE population and highlights its often unnoticed symptoms, urging awareness due to potential long-term health consequences; it provides no new results.
522 citations
,
January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
136 citations
,
April 2010 in “British Journal of Dermatology” This review discusses guidelines for acitretin use in dermatology, reporting its efficacy in severe psoriasis and recommendations for combination therapies, without providing new clinical trial results.
11 citations
,
September 2012 in “Journal of obstetrics and gynaecology Canada” This review examines the scientific evidence on the short-term safety of testosterone therapy for treating hypoactive sexual desire disorder in women, without presenting new clinical results.
4 citations
,
December 2022 in “Frontiers in cell and developmental biology” This review discusses the use of zebrafish larvae as an alternative model for studying ototoxicity, facilitating large-scale screening for otoprotective compounds, but reports no new clinical results.
June 2018 in “Reactions Weekly” A 65-year-old man developed a serious skin cancer linked to a drug he was taking for a fungal infection after a bone marrow transplant.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
30 citations
,
January 1994 This study found that oral administration of Lactococcus lactis subsp. cremoris H61 to aged mice was associated with reduced bone loss, fewer skin ulcers, and less hair loss compared with controls.
28 citations
,
August 2000 in “Current Opinion in Chemical Biology” This article reviews current osteoporosis treatments, focusing on the potential of selective androgen receptor modulators and other agents to enhance bone formation, but provides no new clinical data.
November 2024 in “Revista de Investigación y Educación en Ciencias de la Salud (RIECS)” In this case study, a 7-year-old girl was diagnosed with Isolated Premature Pubarche after presenting with pubic hair growth and normal hormonal and bone age assessments.
December 1972 in “Archives of Dermatology” This report describes a case of scarring alopecia in a 7-year-old girl, highlighting the presence of inflammation without true sclerosis despite normal bone age and negative fungal tests.
1 citations
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August 2025 in “Journal of Diabetes and its Complications” This review found that among young adults with type 1 diabetes, hearing loss prevalence ranged from 22.6% to 48.0% and was associated with age, diabetes duration, and systolic blood pressure, while peridontitis and alveolar bone loss also showed varying prevalence patterns.
36 citations
,
October 2016 in “Bone” This case report describes a male patient with aromatase deficiency, revealing that a c.628G>A mutation can lead to varied clinical features, such as low bone mass and normal metabolic profiles.
53 citations
,
November 2014 in “International Journal of Oncology” This study found that wedelolactone, a natural compound from plants, inhibited breast cancer-mediated osteoclast differentiation and activity in vitro, suggesting its potential as a therapy for bone destruction in breast cancer bone metastasis.
38 citations
,
April 2005 in “Journal of Investigative Dermatology” Human hair follicle cells can become fat and bone cells, useful for therapy.
14 citations
,
January 2017 in “Elsevier eBooks” This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.
April 2023 in “Acta Scientific Orthopaedics” This essay discusses hair loss due to head bone displacement and does not report new clinical results, building on the author's prior work regarding the natural process of growth-related changes.
January 2017 in “Journal of Antivirals & Antiretrovirals” This retrospective study observed that breast cancer treatments disrupted normal blood counts and led to bone marrow suppression, highlighting the need for nutritional counseling to improve patient quality of life.
66 citations
,
December 1999 in “Journal of Investigative Dermatology” New mutations in the hairless gene may cause hair loss and affect bone development.
1 citations
,
September 2023 in “Stem cell research & therapy” This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.
This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.
61 citations
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January 2017 in “Human Reproduction Open” This review discusses hormone replacement therapy for women with premature ovarian insufficiency, strongly recommending it for symptom relief and bone protection, but notes a lack of evidence on optimal types and doses.
62 citations
,
December 1995 in “The Journal of Clinical Endocrinology & Metabolism” This study found that combining a GnRH agonist with a low-dose oral contraceptive was more effective in treating hirsutism than either agent alone and prevented hypoestrogenic side effects.
2 citations
,
September 2022 in “Annals of Medicine and Surgery” The researchers reported a rare case of invasive cutaneous squamous cell carcinoma of the scalp extending into bone and dura mater, successfully treated with surgery and skin flap repair, without metastasis observed at three months.
1 citations
,
January 2024 in “Nature communications” This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.
13 citations
,
November 2023 in “International Journal of Nanomedicine” This review explores the potential of nanofiber scaffolds as an advanced intervention in peripheral nerve regeneration, detailing their fabrication, cellular interactions, controlled bioactive agent release, clinical translation prospects, emerging trends, and biocompatibility considerations for treating peripheral nerve injuries.
2 citations
,
June 2022 in “대한스포츠의학회지” This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.
October 2024 in “Journal of the Endocrine Society” This case study reports on a rare form of vitamin D resistant rickets in a 37-year-old male, highlighting the condition's clinical features and the necessity for a thorough understanding of calcium and vitamin D metabolism in the diagnosis and management of metabolic bone diseases.
October 2008 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report describes a 20-month-old female with a rare adrenocortical virilizing tumor, successfully treated with surgery, showing no pathological lesions over a 10-year follow-up.