Search
for

    Sort by

    Research

    210-240 / 1000+ results
      The PDGF/PDGFR Pathway as a Drug Target

      research The PDGF/PDGFR pathway as a drug target

      182 citations , November 2017 in “Molecular Aspects of Medicine”
      This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

      research A Hot New Twist to Hair Biology

      174 citations , April 2005 in “˜The œAmerican journal of pathology (Print)”
      This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.
      Interventions for Alopecia Areata

      research Interventions for alopecia areata

      164 citations , April 2008 in “Cochrane library”
      This review of interventions for alopecia areata found no significant treatment benefits for hair growth compared to placebo, indicating a need for larger, well-conducted studies.
      Decreased Serum Ferritin Is Associated With Alopecia in Women

      research Decreased Serum Ferritin is Associated With Alopecia in Women

      163 citations , November 2003 in “Journal of Investigative Dermatology”
      This study found that women with androgenetic alopecia or alopecia areata have significantly lower serum ferritin levels than those without hair loss, suggesting a potential link between these types of alopecia and decreased iron stores.
      Probing the Effects of Stress Mediators on the Human Hair Follicle

      research Probing the Effects of Stress Mediators on the Human Hair Follicle

      159 citations , November 2007 in “American Journal of Pathology”
      In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      Androgens and Human Hair Growth

      research Androgens and human hair growth

      157 citations , April 1994 in “Clinical endocrinology”
      Androgens can cause hair growth in some areas and hair loss on the scalp.
      Molecular Biology of Hair Morphogenesis: Development and Cycling

      research Molecular biology of hair morphogenesis: Development and cycling

      155 citations , August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution”
      This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.
      Minoxidil Use in Dermatology, Side Effects, and Recent Patents

      research Minoxidil Use in Dermatology, Side Effects and Recent Patents

      152 citations , April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery”
      This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.
      Alopecia Areata: Overview and Treatment Options

      research Alopecia areata

      151 citations , February 2007 in “International Journal of Dermatology”
      This review explores the causes and mechanisms of alopecia areata and discusses current treatments, reporting no new clinical findings.
      Bioprinting of Skin Constructs for Wound Healing

      research Bioprinting of skin constructs for wound healing

      150 citations , January 2018 in “Burns & Trauma”
      This review discusses strategies and advances in bioprinting for skin wound healing, concluding that bioprinting could offer promising solutions for skin regeneration despite existing challenges.
      Theoretical Considerations in Laser Hair Removal

      research Theoretical considerations in laser hair removal

      150 citations , April 1999 in “Dermatologic Clinics”
      This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
      Cutaneous Lupus Erythematosus: A Review

      research Cutaneous lupus erythematosus: a review

      149 citations , July 2002 in “Dermatologic clinics”
      This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      Ichthyosis

      research Ichthyosis

      147 citations , January 2003 in “American journal of clinical dermatology”
      This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
      The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.
      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      Lupus Erythematosus: Systemic and Cutaneous Manifestations

      research Lupus erythematosus: systemic and cutaneous manifestations

      144 citations , September 2006 in “Clinics in Dermatology”
      This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.