286 citations,
April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
284 citations,
February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
21 citations,
March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
3 citations,
November 2005 in “Women's health” Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
1 citations,
August 2023 in “Curēus” Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
1 citations,
January 2006 Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
31 citations,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
28 citations,
May 2018 in “Scientific reports” Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
20 citations,
September 2010 in “Cell Cycle” Mice can regenerate ear tissue without the p53 protein.
15 citations,
June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
12 citations,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
11 citations,
February 1980 in “BMJ. British medical journal” Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.
9 citations,
March 2001 in “Clinics in dermatology” Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
8 citations,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
January 2024 in “Diabetes & metabolism journal” Disrupting natural body clocks increases the risk of developing type 2 diabetes.
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
Optical Coherence Tomography has potential in diagnosing hair loss and monitoring blood clotting, and could be improved for deeper tissue observation and better hair loss understanding.
July 2015 in “Cambridge University Press eBooks” The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
131 citations,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
101 citations,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
80 citations,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
54 citations,
August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
49 citations,
April 2016 in “International journal of molecular sciences” Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.
27 citations,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
18 citations,
December 2014 in “Obstetrics and Gynecology Clinics of North America” Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
16 citations,
July 2020 in “Advanced functional materials” 3D cell-derived matrices improve tissue regeneration and disease modeling.