69 citations
,
September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
59 citations
,
February 2012 in “Journal of Dermatological Science” This review discusses the multiple layers of environmental controls on hair stem cell homeostasis and suggests that targeting these layers could offer safer regenerative medicine therapies without directly using stem cells.
42 citations
,
May 2016 in “Annual Review of Cell and Developmental Biology” This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.
41 citations
,
June 2018 in “Medicine Health Care and Philosophy” This article proposes criteria to differentiate between medicalization and over-medicalization, examining the consequences and ethical considerations of misidentifying medical issues, and suggests guideline questions to help draw clearer boundaries in medicine.
41 citations
,
March 2017 in “PLoS neglected tropical diseases” This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.
28 citations
,
September 2020 in “Pharmaceutics” This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.
27 citations
,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.
24 citations
,
July 2019 in “Journal of Obstetrics and Gynaecology” This study found that a 12-week supplementation with a combination of insulin sensitizing agents, antioxidants, and vitamins significantly improved menstrual cyclicity, acne, and hirsutism in women with PCOS, with additional weight loss benefits in obese subjects.
22 citations
,
January 2017 in “Indian Dermatology Online Journal” This review discusses the use of follicular unit extraction for hair restoration using body hair, reporting no new clinical findings, and highlights its potential for advanced baldness cases with limited scalp donor hair.
20 citations
,
April 2022 in “Journal of Personalized Medicine” This study found that robotic training with the Ekso-GT significantly improved body representation and quality of life in spinal cord injury patients compared to conventional physical therapy.
20 citations
,
June 2010 in “Genes and Immunity” This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.
18 citations
,
January 2020 in “Ecology and evolution” This study analyzed gene expression changes during the autumn coat color change in mountain hares and found conserved gene regulation with snowshoe hares, highlighting its role in seasonal camouflage adaptation.
18 citations
,
September 2018 in “Experimental physiology” This study observed that electro-acupuncture reduced global DNA methylation and DNMT3b expression in a PCOS-like rat model, suggesting a role of hypothalamic DNA methylation in PCOS development and treatment.
18 citations
,
July 2010 in “Expert Review of Endocrinology & Metabolism” This study identified an association between the FTO gene and susceptibility to PCOS, providing the first genetic evidence linking PCOS to obesity.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
12 citations
,
November 2019 in “PLoS ONE” This study suggests a weak association between male-pattern baldness and some coronary heart disease risk factors, but does not support it as a strong indicator of coronary risk.
11 citations
,
March 2021 in “Dermatology and therapy” This study developed the Alopecia Areata Patient Priority Outcome (AAPPO), a new tool designed to measure and capture the symptoms and impacts of alopecia areata that matter most to patients.
11 citations
,
May 2020 in “Frontiers in psychiatry” This study found that experiencing childhood abuse is associated with higher BMI, but hair cortisol and cortisone do not mediate this relationship.
6 citations
,
July 2007 in “Developmental Dynamics” This study reports that Wise is expressed in specific patterns during the morphogenesis of chick embryos, particularly in regions associated with known signaling molecules like Wnt, Bmp, and Shh.
4 citations
,
June 2019 in “Revista brasileira de ginecologia e obstetrícia” This article discusses the prevalence of hirsutism in women and highlights that many cases exhibit normal androgen levels, suggesting a need for broader diagnostic approaches.
3 citations
,
July 2025 in “International Journal of Biological Sciences” This review highlights that the RNA modification N6-methyladenosine (m6A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.
2 citations
,
June 2016 in “Dermatologic Clinics” This article reviews clinical practice gaps in dermatology regarding the care of patients with hair disorders, including attitude, knowledge, and skill deficiencies, and reports no new results.
2 citations
,
August 2014 in “Journal of The American Academy of Dermatology” Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.
1 citations
,
September 2023 in “Journal of drugs in dermatology” This article discusses the perspectives of clinicians and patients on alopecia areata, an autoimmune disorder with significant psychosocial impacts, highlighting the unpredictability and limited effectiveness of current treatments as well as the key unmet needs and gaps in care.
1 citations
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April 2020 in “medRxiv (Cold Spring Harbor Laboratory)” This study identified gene sets associated with Tourette Syndrome, implicating Ligand-gated Ion Channel Signaling, Lymphocytic, and Cell Adhesion and Trans-synaptic Signaling processes in the disorder's neurobiology.
1 citations
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November 1992 in “Indian Dermatology Online Journal” This review discusses the use of follicular unit extraction for hair restoration, particularly body hair transplantation, and highlights its potential as an alternative donor source in advanced baldness cases, but reports no new clinical findings.
July 2026 in “Journal of Reproductive and Infant Psychology” This study explored postpartum body image and menstruation experiences among 11 UK mothers, identifying themes of body dissatisfaction and the stress of resumed menstruation, while highlighting the need for better healthcare support and the positive role of reframing body perceptions towards functionality.
July 2026 in “Quality in Sport” This narrative review highlights that endurance, skill-oriented athletes, and physique-oriented competitors such as bodybuilders face accelerated degradation of fillers and botulinum neurotoxin due to elevated basal metabolic rates and other factors, and raised concerns about psychological conditions like body dysmorphic disorder in these populations.
March 2026 in “International Journal of Science Strategic Management and Technology” This research introduces WomenCare, a web-based system using a machine learning model to predict PCOD risk by evaluating factors like age, BMI, and lifestyle habits; it aims to help women monitor their health but is not a substitute for a professional diagnosis.
December 2025 in “Therya notes” In this study, researchers documented the first instance of alopecia in bats within the Puebla region, specifically affecting two Artibeus jamaicensis and one Choeronycteris mexicana, possibly linked to environmental stress from human activities interfering with their nutrition.