106 citations,
January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
55 citations,
November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
51 citations,
June 2016 in “Journal of the European Academy of Dermatology and Venereology” Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.
48 citations,
May 1999 in “International Journal of Dermatology” Alopecia areata is an unpredictable autoimmune hair loss condition, treated based on severity, with half of patients regrowing hair within a year without treatment.
26 citations,
August 2016 in “Actas Dermo-Sifiliográficas” Frontal Fibrosing Alopecia in men is often missed and can come with symptoms like facial bumps and hair loss on eyebrows and limbs.
26 citations,
January 2016 in “Journal of cutaneous and aesthetic surgery” Hair transplant combining scalp and beard hair with PRP was successful for scarring alopecia.
24 citations,
June 2016 in “Acta dermato-venereologica” Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” A mix of methotrexate, corticosteroids, and topical minoxidil effectively treated severe total body hair loss, but caused stretch marks and needs long-term monitoring.
179 citations,
December 2004 in “Journal of The American Academy of Dermatology” Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.
March 2023 in “Scientific reports” Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
July 1980 in “Journal of The American Academy of Dermatology” The conference concluded that understanding hair and nail disorders is important, iron deficiency may be linked to hair loss, and while some treatments for skin conditions are effective, they may have risks and high costs.
8 citations,
January 2003 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” Chemotherapy may cause recurring hair loss due to an autoimmune response.
3 citations,
January 2016 in “Elsevier eBooks” Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
July 2015 in “Actas Dermo-Sifiliográficas” A woman experienced excessive hair growth after using a hair loss treatment with minoxidil.
42 citations,
July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
17 citations,
November 2018 in “Dermatology” Most patients with frontal fibrosing alopecia had facial bumps, with Hispanic/Latino and premenopausal women being more affected, suggesting a more severe condition.
January 2014 in “Cosmoderma” The document concludes that personalized treatment plans for hair loss in Asian men are necessary and more research is needed to develop effective guidelines.
25 citations,
November 2013 in “Journal of the American Academy of Dermatology” Many patients on new leukemia drugs had mild to moderate skin reactions.
1 citations,
December 2017 in “Anais Brasileiros de Dermatologia” Frontal fibrosing alopecia can mimic traction alopecia but has distinct features like facial papules and eyebrow thinning.
5 citations,
April 2007 in “Expert Review of Dermatology” Dermatologists can help detect and manage eating disorders by recognizing skin changes.
69 citations,
December 2006 in “Archives of dermatology” Adalimumab may cause severe hair loss in some patients.
36 citations,
January 2010 in “International Journal of Trichology” Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
May 1991 in “Current problems in dermatology” Skin issues can indicate immune system problems.
5 citations,
September 2021 in “Journal of The American Academy of Dermatology” Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
January 2024 in “Pan African Medical Journal” Non-scarring hair loss is common in lupus patients and can be diagnosed with specific hair and tissue tests.
20 citations,
June 2019 in “Experimental Dermatology” The research suggests that autophagy-related genes might play a role in causing alopecia areata.
176 citations,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
60 citations,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
13 citations,
August 2020 in “Mayo Clinic proceedings” Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.
7 citations,
January 2012 in “International Journal of Trichology” Two siblings both had a rare case of alopecia areata at the same time.