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Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.

Current treatments for alopecia show no significant long-term benefits.

Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.

Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Both gene and non-gene areas of DNA evolved to make some mammals hairless.

Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Both concentrations of triamcinolone acetonide are effective for hair regrowth in patchy alopecia areata, but 5 mg/mL is recommended to reduce side effects.

hsa-miR-193a-5p may help diagnose and treat alopecia areata.

Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.

Oral minoxidil has more side effects but can be more effective than topical minoxidil.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Hairless protein can block vitamin D activation in skin cells.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Pregnancy can cause normal skin changes that usually go away after childbirth and don't need treatment.

Future clinical uses of Intense Pulsed Light (IPL) are likely to grow and become more effective with new advancements and combined treatments.

Ketoconazole can treat ovarian hyperandrogenism but should be used cautiously with monitoring and birth control.

Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.

Effective treatment guidelines for frontal fibrosing alopecia are still unclear.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

PCOS is a common inherited condition causing cysts, irregular periods, and increased diabetes risk in women.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Oral tofacitinib may be an effective future treatment for children with severe alopecia areata, but more research is needed.

DPCP is effective for treating severe alopecia areata, but relapse is common.

New treatments for alopecia areata show promise, but standardized guidelines are needed.

The document concludes that hirsutism in women, often caused by PCOS, requires systematic evaluation and can be treated with medications, mechanical removal, or cosmetic methods, with weight loss also being beneficial.

Hirsutism greatly lowers the quality of life for Turkish women.