research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
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research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis
Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
research Effect of a Low-Starch/Low-Dairy Diet on Fat Oxidation in Overweight and Obese Women with Polycystic Ovary Syndrome
A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.
research Optimization of Lipid-Based Nanoformulation for Cutaneous Targeting: Niosomes as Potential Candidates
Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.
research Human Hair Follicles Operate a Functional Peripheral Equivalent of the Hypothalamic-Pituitary-Somatotropic Axis Ex Vivo
Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
research Polycystic Ovary Syndrome: Comprehensive Management and Health Impacts
PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.
research Role of Diet in Acne
Eating nuts, chocolate candy, and red tea might worsen acne, while eating more fresh vegetables could reduce it.
research Patient Care
The Beverly Hills Diet is unhealthy and can cause serious health issues; pharmacists should advise against it and asthmatics should avoid nonprescription antihistamines.
research Skin Cancers and Their Risk Factors in Older Persons: A Population-Based Study
Older men and those with outdoor jobs are at higher risk for skin cancer; early full-body skin checks are recommended for early detection.
research Combination Use of Triamcinolone Acetonide and Immunotherapy as a New Therapeutic Option in Alopecia Totalis
Combining triamcinolone acetonide with immunotherapy can help regrow hair in some alopecia totalis patients.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes
Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
research Whole Genome Scan and Selection Signatures for Climate Adaptation in Yanbian Cattle
The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.
research Treatment Pearls From Europe
European dermatologic treatments focus on lifestyle and psychosocial factors, use diverse methods like baths and climate therapy, and emphasize the importance of diet and supplements for skin health.
research Alopecia in a 19-Month-Old Boy
A 19-month-old boy with a rare hair disorder showed mild improvement with treatment, but his family chose gentle hair care due to limited success.
research Food Administration and Not Genetic Variants Causes Pharmacokinetic Variability of Tadalafil and Finasteride
Food intake, not genetics, affects how the body processes tadalafil and finasteride.
research The Effects of Glehnia Littoralis and Andrographis Paniculata Extract on Hair Growth in Human Follicle Dermal Papilla Cells
Glehnia littoralis and Andrographis paniculata extracts can significantly boost hair growth.
research The Endocrine Function Of The Skin: An Analytical Narrative
The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.
research Selenium's Role on Thyroid Autoimmunity and Cognitive Dysfunction in Elderly
Selenium helps prevent thyroid issues and cognitive decline in the elderly, but balance is key.
research Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair
Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
research Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases
Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.
research Burn Reconstruction: The Problems, Techniques, and Applications
Burn reconstruction improves with new techniques, materials, and tissue engineering.
research Influence of Spironolactone Treatment on Endothelial Function in Non-Obese Women with Polycystic Ovary Syndrome
Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
research Primary Generalized Glucocorticoid Resistance And Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
research Combined Hormonal Contraception and Venous Thromboembolism
Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
research Efficacy of Bergamot: From Anti-Inflammatory and Anti-Oxidative Mechanisms to Clinical Applications as a Preventive Agent for Cardiovascular Morbidity, Skin Diseases, and Mood Alterations
Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Evaluation of BMI as a Risk Factor for Complications Following Gender-Affirming Penile Inversion Vaginoplasty
BMI is not a significant predictor of complications after gender-affirming penile inversion vaginoplasty.