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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Testosterone improves mood and thinking skills; finasteride has no effect.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Eating raw cheonggukjang improves scalp hair in middle-aged women.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Celiac disease requires more than just a gluten-free diet for effective management.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

A small dose of Platycladus orientalis leaf extract improves raccoon dogs' growth and health, but higher doses can be harmful.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Glycerin in hand cream can cause allergic skin reactions.

Managing PCOS effectively requires focusing on psychological health, lifestyle changes, and medication.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Probiotics show promise for health benefits but need more research to understand how they work.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.

The conclusion is that certain surgeries can help people with gender dysphoria look more like their true gender and feel better.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.