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New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Hair loss caused by genetics and hormones; more research needed for treatments.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Mutant mice help researchers understand hair growth and related genetic factors.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

A20 protein is crucial for normal skin and hair development.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.

TGF-β2 plays a key role in human hair growth and development.