29 citations
,
July 2012 in “Fertility and Sterility” This study observed that hepatotoxicity is a rare but possible event in hyperandrogenic young females treated with low- and ultralow-dose flutamide, regardless of dose or oral contraceptive use.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
12 citations
,
November 2019 in “PLoS ONE” This study suggests a weak association between male-pattern baldness and some coronary heart disease risk factors, but does not support it as a strong indicator of coronary risk.
11 citations
,
March 2021 in “Reproductive Biology and Endocrinology” This study found that bloating is the most frequently reported symptom and a main predictor of polycystic ovary syndrome among women using the Flo app across five countries.
9 citations
,
January 2022 in “Reproductive Biology and Endocrinology” This study aimed to identify reliable predictors for the effectiveness of metformin therapy in weight loss and reduction of plasma androgen levels in PCOS women, highlighting the unpredictability of response to treatment.
7 citations
,
October 2020 in “Journal of Clinical Medicine” In this study, researchers found that overweight and obese women with polycystic ovary syndrome showed adverse changes in glucose metabolism over time, highlighting the importance of early intervention to prevent cardiometabolic diseases.
April 2026 in “Frontiers in Medicine” In this study, young female medical students at King Saud University reported a higher prevalence of physician-diagnosed PCOS compared to similar Western populations, and hirsutism was notably associated with the condition, highlighting the need for early screening and health education.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
May 2024 in “IP Journal of Nutrition Metabolism and Health Science” This study found that an educational program significantly improved knowledge about polycystic ovary syndrome and its prevention among adolescent girls at a selected college.
379 citations
,
May 2016 in “Cochrane library” This review concluded that corticosteroids improve muscle strength and function in boys with Duchenne muscular dystrophy over short-term periods, but evidence on prolonging walking ability remains insufficient, and side effects are common.
198 citations
,
July 2011 in “Cochrane library” This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.
155 citations
,
March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
53 citations
,
January 2012 in “Fertility and Sterility” This study found that women with polycystic ovary syndrome have a higher risk for obstructive sleep apnea, primarily due to the prevalence of severe obesity, rather than the syndrome itself.
16 citations
,
June 2005 in “Clinical and Experimental Dermatology” In this study of 30 severe anorexia nervosa patients, true acquired pili torti was not found although twisted hair was observed in 6.6% of cases.
12 citations
,
August 2019 in “BMC Medical Genetics” This study found that two MC4R gene polymorphisms are associated with higher BMI in women with PCOS in western Saudi Arabia, but are not linked to PCOS itself.
7 citations
,
January 2022 in “Evidence-based complementary and alternative medicine” This study found that ginger supplementation significantly improved persistent hypothyroid symptoms and may aid in weight and lipid profile management in hypothyroid patients with normal TSH levels.
6 citations
,
January 2018 in “Dermato-endocrinology” This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.
5 citations
,
June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” This study found that women with polycystic ovary syndrome have higher triglyceride and fasting glucose levels in obese individuals and higher total cholesterol levels in non-obese individuals compared to healthy women.
5 citations
,
December 2016 in “Journal of skin and stem cell” This study found that patients with cutaneous lichen planus had a higher risk of metabolic syndrome, dyslipidemia, diabetes mellitus, and hypertension compared to controls.
4 citations
,
January 2015 in “Indian Journal of Dermatology” This study reports that severe androgenic alopecia prevalence in young Caucasian men increases with age, varies by region, and that body mass index may be a risk factor.
2 citations
,
November 2024 in “Clinical Cosmetic and Investigational Dermatology” This Mendelian randomization study suggests a causal link between higher BMI and increased risk of psoriasis, atopic dermatitis, and hidradenitis suppurativa, potentially due to elevated biomarkers such as triglycerides and C-reactive protein.
2 citations
,
December 2021 in “Scientific reports” In this study, scalp hair sweating was a significant predictor of hair cortisol levels in healthy adults, while BMI and perceived stress, although associated, did not significantly predict cortisol levels.
January 2023 in “Journal of The American Academy of Dermatology” This study examined medical comorbidities and medications among women with vulvar lichen sclerosus, contributing insights for comprehensive treatment strategies, but does not report new clinical results.
69 citations
,
September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
21 citations
,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
7 citations
,
February 2018 in “International Journal of Research in Medical Sciences” This study reported that polycystic ovarian syndrome is common among women with adult onset acne, with obesity and hirsutism showing significant associations.
2 citations
,
August 2014 in “Journal of The American Academy of Dermatology” Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.
1 citations
,
January 2020 In this study, researchers found that serum anti-Mullerian hormone levels in adolescents with polycystic ovary syndrome were not influenced by body mass index.
1 citations
,
January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.