February 2017 in “The Journal of Sexual Medicine” This study found that young men using finasteride for androgenic alopecia exhibited erectile tissue fibrosis and associated sexual dysfunction, including low libido and mood changes.
491 citations
,
July 2000 in “The Journal of Clinical Endocrinology and Metabolism” This study found that the prevalence of polycystic ovary syndrome was 6.5% in a minimally biased sample of Caucasian women from Spain.
356 citations
,
September 2014 in “Journal of Clinical Research in Pediatric Endocrinology” This article discusses the rising prevalence and serious implications of childhood obesity and reports no new experimental findings; the authors emphasize the importance of prevention and early intervention through comprehensive management programs.
166 citations
,
March 2007 in “Hypertension” In this study, hyperandrogenemia in young women with polycystic ovary syndrome was linked to higher blood pressure, independent of factors like age, insulin resistance, obesity, or dyslipidemia.
149 citations
,
December 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
145 citations
,
March 2010 in “Fertility and Sterility” This study reported that ovulatory PCOS is a milder form of the condition compared to classic PCOS phenotypes, which share similar clinical and hormone characteristics.
114 citations
,
March 2018 in “PLOS Medicine” This study found that women with polycystic ovary syndrome have higher rates of nonalcoholic fatty liver disease, with androgen excess contributing to the risk.
75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that combining low-dose spironolactone with metformin provided greater clinical benefits and improved treatment compliance in women with PCOS compared to either drug alone.
66 citations
,
December 2003 in “Endocrinology and Metabolism Clinics of North America” This article emphasizes the need for physicians to gain expertise in obesity care, detailing comprehensive assessments as critical for effective management, but provides no new research findings.
62 citations
,
June 2023 in “Acta Dermato Venereologica” This observational study found that patients with various skin diseases across 17 European countries experience higher levels of perceived stigmatization than skin-healthy controls, particularly those with psoriasis, atopic dermatitis, alopecia, and bullous disorders, with factors such as disease severity and psychological distress influencing stigmatization levels.
62 citations
,
July 2017 in “Endocrine connections” This meta-analysis reported a significant association between polycystic ovary syndrome and an increased risk of obstructive sleep apnea in adult patients.
61 citations
,
April 2021 in “Frontiers in Medicine” This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.
60 citations
,
May 2011 in “Endocrinology and Metabolism Clinics of North America” This article discusses the association between hypertension and polycystic ovary syndrome, highlighting the need for managing related risk factors, but reports no new clinical results.
52 citations
,
November 2009 in “International journal of gynaecology and obstetrics” This study found that hyperandrogenemia in Chinese women with PCOS is associated with higher risks of type 2 diabetes and obesity, suggesting it should be prioritized in managing PCOS-related infertility.
48 citations
,
September 2009 in “Dermato-endocrinology” This article reviews skin signs in patients with anorexia nervosa and their potential role in early diagnosis but reports no clinical results; it emphasizes the importance of dermatologists in recognizing these signs.
46 citations
,
August 2016 in “Journal of The American Academy of Dermatology” This study found that lifestyle factors such as diet, personal history, and psychological stress may be linked to the development of adult female acne, based on observed associations in a case-control setting.
46 citations
,
January 2007 in “The European Journal of Contraception & Reproductive Health Care” This review discusses the increased risk of venous thromboembolism associated with combined hormonal contraceptives, particularly noting higher risks with certain progestins like desogestrel, gestodene, and cyproterone acetate, but reports no new clinical findings.
45 citations
,
February 2011 in “Journal of the European Academy of Dermatology and Venereology” This study found that patients with lichen planus had significantly higher levels of triglycerides, total cholesterol, and LDL-C, and lower HDL-C compared to healthy controls, suggesting an association with dyslipidaemia.
42 citations
,
August 2017 in “Human Reproduction” This study observed that a longer anterior clitoral anogenital distance (AGDAC) is associated with polycystic ovary syndrome in adult Mediterranean women.
41 citations
,
September 2014 in “Journal of Pharmacy and Pharmacology” This study found that melatonin significantly improved metabolic and reproductive parameters in PCOS-induced rats, with effects similar to metformin.
40 citations
,
January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
39 citations
,
January 2004 in “Physiological Research” In this study, researchers reported that about one-third of men with premature alopecia displayed hormonal shifts and higher insulin resistance, resembling the prevalence pattern of PCOS in women.
35 citations
,
May 2015 in “Arquivos De Gastroenterologia” This study reported that almost 25% of women with PCOS were diagnosed with NAFLD, and 32.7% to 44.6% had metabolic syndrome, with higher prevalence in those with both conditions.
31 citations
,
December 2010 in “International Journal of Andrology” This study found that male pattern baldness and a history of severe acne were inversely associated with testicular germ cell tumors, while taller height showed a positive association.
30 citations
,
January 2019 in “Clinical Endocrinology” This study observed that serum AMH concentration and LH/FSH ratio showed comparable diagnostic value for PCOS among infertile women, though neither is adequate alone for diagnosis.
29 citations
,
October 2020 in “Journal of the European Academy of Dermatology and Venereology” This article is a discussion piece that examines the clinical symptoms of hyperandrogenic women with COVID-19, without reporting new research findings.
29 citations
,
July 2020 in “Journal of The American Academy of Dermatology” In this study, researchers found that severe androgenic alopecia in hospitalized men was associated with a higher likelihood of testing positive for COVID-19.
29 citations
,
March 2015 in “Clinical Endocrinology” This study found that women with polycystic ovary syndrome in the UK show significant differences in phenotypic and metabolic characteristics based on ethnicity, age, and obesity, influencing management strategies.
28 citations
,
January 2017 in “Obstetrician & gynaecologist/The obstetrician & gynaecologist” This article discusses the complexities of diagnosing and managing polycystic ovary syndrome, highlighting the challenges related to fertility treatment criteria, insulin resistance, and long-term health implications, but reports no new clinical findings.
26 citations
,
October 2016 in “Clinics in Dermatology” This article discusses various hormonal therapies for acne and provides practical treatment guidelines for managing hormonally related acne, but it reports no new research findings.