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PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Different types of skin cells play specific roles in development, healing, and cancer.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Finasteride safely lowers DHT levels without affecting testosterone.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Liposomes could improve how skin care products work but are costly and not very stable.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

DHT may increase the risk of heart disease and death in elderly men.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Nanoparticle systems make cancer treatment less toxic.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Long-term parenteral nutrition without zinc can cause severe zinc deficiency.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Minoxidil use increases facial hair growth in females, more in older users.