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Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Wool follicles are complex, involving interactions between different cell types and structures.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.

Minoxidil promotes hair growth but stops working when discontinued.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.

Dermoscopy improves diagnosis and treatment monitoring for children's skin infections, inflammations, and hair disorders.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Apoptosis is crucial for healthy skin and treating skin diseases.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.