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This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.

This research abstract provides no results, focusing on the equal contributions of the authors in the field of molecular, cellular, and developmental biology from Yale University.

In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.

This review discusses the JAK-STAT pathway and the use of FDA-approved JAK inhibitors for autoimmune and inflammatory diseases but reports no new research findings.

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

This review discusses the complex relationship between stress and various skin conditions, highlighting the role of the skin in the stress response and the brain-skin communication pathways, but reports no new research findings.

This study found that mice deficient in ceramide synthase 4 showed altered sebum composition and progressive hair loss due to obstructed hair canals.

This review examines the roles of Smad-4 and Smad-7 in hair follicle differentiation and development through BMP signaling and TGFβ/Activin/BMP pathway inhibition but reports no new experimental results.

This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.

In this mouse study, the researchers found that the monoclonal antibody ME1 causes hair follicle inflammation by up-regulating TNFα, which can be reduced by TNFα and interleukin-1 inhibitors.

Hidradenitis suppurativa improves with antiandrogen therapy.

This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.

In this study, transgenic mice with Rank expression in hair follicles showed excessive lymph node growth, which could be normalized by neutralizing the overproduced RANKL, underscoring its role in immune system regulation.

In this study, Proxalutamide significantly increased the rate of viral clearance and reduced clinical remission time in patients with mild to moderate COVID-19 compared to placebo.

This review discusses current and potential treatments for alopecia areata, focusing on immunosuppressive and immunomodulatory approaches, but provides no new clinical results.

This study found that activin B promotes epithelial wound healing in mice through the RhoA-Rock-JNK-cJun signaling pathway, suggesting a potential therapeutic role for activin B in wound repair.

This case report highlights a woman who developed new-onset alopecia areata after starting adalimumab for psoriatic arthritis, challenging the assumed role of TNF-alpha in the condition's pathogenesis.

This study indicates that progesterone’s anesthetic activity in PR knockout mice is not due to progesterone receptors but is partially mediated by the neurosteroid allopregnanolone through GABAA receptor potentiation.

This study validated a protocol for inducing surface ectoderm differentiation from human induced pluripotent stem cells and highlighted the role of TGFβ signaling pathways in this process.

This study describes molecular mechanisms explaining how sex and stress steroids rapidly modulate dendritic spine formation in hippocampal neurons, suggesting recovery-like effects under steroid-depleted conditions compared to intact conditions.

In this study, petroleum ether extract of Citrullus colocynthis fruit effectively promoted hair growth in a mouse model of androgen-induced alopecia, showing comparable results to the standard treatment, finasteride.

This article discusses the synthesis and action of testosterone and its interaction with specific receptors, reporting no new research findings.

This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.

This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.

This review discusses rodent models of alopecia areata and suggests they are crucial for understanding the autoimmune mechanisms and potential treatments but reports no new clinical results.

In this study, inhibition of neurosteroid synthesis after inducing status epilepticus in rats led to acute seizures and accelerated the onset of epilepsy, suggesting a role for δ-GABAR plasticity in epileptogenesis.

This review discusses the role of androgen hormones in skin and hair conditions and highlights the potential of antiandrogen therapies in dermatology, reporting no new results.