June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.
49 citations
,
July 2004 in “Anesthesiology” This review discusses pharmacologic treatment options for muscle-related pain conditions and notes that there is strong evidence for the efficacy of tricyclic antidepressants and muscle relaxants in specific myofascial pain syndromes, but not universally.
14 citations
,
July 1987 in “Dermatologic Clinics” This article reviews current evaluation and treatment options for androgenic alopecia in women and reports no new clinical results.
This review discusses supplements used to alleviate side effects of chemotherapy, highlighting various natural remedies, but reports no original clinical research findings.
1 citations
,
December 1997 in “The British Journal of Psychiatry” This document outlines the indications, dosing, side effects, and contraindications for Epilim in epilepsy treatment, with no new research findings presented.
14 citations
,
January 2016 in “Experimental Dermatology” This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.
13 citations
,
March 1990 in “JAMA” This study found that in a small cohort of patients with infections, tumor necrosis factor levels varied, challenging the interpretation that these levels are transient in gram-negative sepsis.
This report adds two cases of total ovarian pigmentation, with no associated symptoms or pathological findings, to the previously reported unilateral case.
102 citations
,
September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
50 citations
,
March 2011 in “European Journal of Endocrinology” This study found that spironolactone treatment can normalize endothelial function and improve cholesterol levels in non-obese patients with polycystic ovary syndrome.
45 citations
,
January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.
29 citations
,
July 1982 in “British Journal of Dermatology” This article discusses hair loss linked to lithium treatment but reports no new clinical findings.
28 citations
,
August 2011 in “Journal of The American Academy of Dermatology” This study found that men with early-onset androgenetic alopecia had significantly larger prostate volumes and lower urinary flow rates compared to healthy controls, suggesting a possible link between AGA and prostate-related urinary symptoms.
25 citations
,
February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.
24 citations
,
January 2003 in “Journal of Investigative Dermatology” In this study, a synthetic antagonist of the p75 neurotrophin receptor was found to significantly inhibit hair follicle regression in murine skin cultures, suggesting a potential role in treating hair disorders characterized by premature catagen entry.
19 citations
,
September 1995 in “Food and nutrition bulletin” This article reviews the toxic effects of mimosine in Leucaena leucocephala and discusses various methods to mitigate its toxicity but presents no new findings.
17 citations
,
January 2010 in “Acta Dermato Venereologica” This report details a case of a 43-year-old woman developing yellowish papular eruptions alongside typical acneiform skin reactions on her cheeks and chest following a switch from cetuximab to panitumumab treatment.
15 citations
,
November 1994 in “International Journal of Dermatology” This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.
14 citations
,
June 2017 in “Immunity” This study found that skin-resident Treg cells regulate hair follicle stem cell proliferation and differentiation through the Jag1-Notch signaling pathway, influencing hair regeneration.
14 citations
,
April 2009 in “Acta Medica Scandinavica” In this study, oral minoxidil combined with other medications improved blood pressure control in patients with severe hypertension but often had to be discontinued due to side effects.
13 citations
,
April 2009 in “Acta Medica Scandinavica” This study found that minoxidil effectively reduced blood pressure in patients with severe hypertension and renal failure resistant to conventional drugs, though side effects like hirsutism and edema were common.
9 citations
,
May 2023 in “Inflammation Research” This study reported that new drugs, despite lower specificity compared to certain immunobiological therapies, are effective across various challenging dermatological diseases, such as psoriasis, psoriatic arthritis, atopic dermatitis, alopecia areata, and vitiligo.
7 citations
,
March 2011 in “Expert Opinion on Drug Safety” This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.
3 citations
,
May 2018 in “Reproductive Sciences” In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.
1 citations
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January 2021 in “Open Access Journal of Cancer & Oncology” In this study, the Trivedi Effect®-Consciousness Energy Healing Treatment was reported to significantly increase the solubility and isotopic abundance ratios of flutamide, potentially improving its stability and efficacy.
June 2026 in “WORLD JOURNAL OF PLASTIC SURGERY” This study highlights that modern facial rejuvenation techniques have shifted toward minimally invasive injectable methods, with botulinum toxin and hyaluronic acid fillers effectively reducing wrinkles, enhancing facial features, and temporarily addressing age-related facial changes as alternatives to more invasive surgery.
This study suggests that 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester from African Yam bean seeds may inhibit the human 5α-reductase II enzyme, potentially helping manage BPH, although further studies are needed.
February 2026 in “Eduvest - Journal Of Universal Studies” This review discusses the molecular mechanisms and therapeutic effectiveness of Janus Kinase Inhibitors for inflammatory skin diseases, suggesting these inhibitors have a rapid onset and favorable safety profile compared to conventional treatments.