research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
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research Adverse Effects and Drug Interactions of Biologic Agents
Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.
research Topical Absorption and Systemic Toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Diffuse Hair Loss in Secondary Syphilis in HIV Positive Man: Case Report
A man with HIV had hair loss due to syphilis, which improved after penicillin treatment.
research An Update on Drug-Induced Pigmentation
Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Total Facelift: Forehead Lift, Midface Lift, and Neck Lift
Facelifts for Asians are challenging due to thicker, heavier skin.
research Micronutrients for Hair and Nails: A Review of Their Impact on Health
Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
research Cutaneous Permeation And Penetration Of Sunscreens: Formulation Strategies And In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research Ptosis in Childhood: Causes, Clinical Presentations, and Management
Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.
research Celiac Disease: Beyond Diet And Food Awareness
Celiac disease requires more than just a gluten-free diet for effective management.
research Obesity in Adults: Position Statement of Various Polish Medical Associations
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Updates in the Understanding and Treatments of Skin and Hair Disorders in Women of Color
New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.
research Epidemiology and Treatment Modalities for the Management of Benign Prostatic Hyperplasia
More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
research Antiandrogen Therapy for Androgenetic Alopecia
Antiandrogen therapy helps treat genetic hair loss.
research Design of Liposome Formulations for CRISPR/Cas9 Enzyme Immobilization: Evaluation of 5-Alpha-Reductase Enzyme Knockout for Androgenic Disorders
New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
research Androgen Effects on the Skin
Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
research Cutaneous Adverse Drug Reactions to Antibiotics: Extent of the Problem
Antibiotics often cause skin reactions, making them a major health concern.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research Minoxidil in Breast Milk
Minoxidil in breast milk may harm nursing infants.
research Comedone Formation: Etiology, Clinical Presentation, and Treatment
Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.
research Deoxycorticosterone’s Anticonvulsant Effects in Infant Rats Are Blocked by Finasteride, but Not by Indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro
The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research TRAIL Sensitization of PC3 Prostate Cancer Cells by Doxorubicin Can Be Blocked by the Antioxidant N-Acetyl-Cysteine or by the Iron Chelator Deferoxamine
Antioxidants can block the cancer-fighting effects of doxorubicin.
research Mechanical Upper Bowel Obstruction Caused by a Large Trichobezoar in a Young Woman: A Very Unusual Case Report
A young woman had surgery to remove a large hairball that blocked her intestines and then got psychiatric help.
research Determination of Permeation Pathway of Gentamicin into Pig's Ear Skin
Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
research Alopecia Secondary to Hyaluronic Acid Embolization: Trichoscopic Findings
Hyaluronic acid injections can cause hair loss due to blocked blood vessels.
research Targeting mTORC1 Suppresses Proliferation of Keratinocyte Stem Cells and Inhibits Skin Tumor Promotion in Mice
Blocking mTORC1 reduces skin tumor growth in mice.