1 citations
,
November 2016 in “Experimental and Therapeutic Medicine” In this study using guinea pigs, the low-dose 800 nm semiconductor laser was found to effectively treat skin blackheads and coarse pores by promoting hair follicle cell apoptosis, while maintaining PCNA expression levels in sebaceous glands.
October 2025 in “Journal of Cosmetic Dermatology” This study found that the AOPT-MTL mode is an effective and safe treatment option for nasal blackheads in Asians, indicating potential for widespread clinical use.
103 citations
,
September 2004 in “Clinics in dermatology” This article discusses methods to measure comedogenesis in acne through the presence of microcomedones and reports no new clinical results; the authors outline a skin surface biopsy technique using cyanoacrylate gel.
47 citations
,
January 2015 in “Dermatology” This review revisits mechanisms underlying acne lesion formation and suggests that preventing comedone development requires controlling critical factors in the pilosebaceous follicle before acne involvement.
45 citations
,
September 2000 in “Archives of dermatology” This study found that 5alpha-reductase type 1 localizes specifically to sebaceous glands in both normal and acne follicles, suggesting its role in sebum regulation.
18 citations
,
April 2002 in “Journal of cutaneous pathology” This study concludes that tiny infundibular cysts, rather than comedones, are the primary lesions in chloracne.
14 citations
,
May 2009 in “Journal of the American Academy of Dermatology” This case study describes a patient with discoid lupus erythematosus whose scalp lesions progressed despite treatment, with findings suggesting inclusion cysts and comedones as part of primary or secondary changes.
13 citations
,
January 2018 in “Skin Appendage Disorders” This study found that dermoscopy improves clinical diagnosis accuracy for trichostasis spinulosa and proposes a new dermoscopic classification with implications for treatment outcomes.
10 citations
,
March 2021 in “International Journal of Environmental Research and Public Health” This study found that Google users are increasingly searching for health information on dermatological issues, with particular interest in itch, hair loss, and skin rash.
7 citations
,
February 2018 in “International Journal of Research in Medical Sciences” This study reported that polycystic ovarian syndrome is common among women with adult onset acne, with obesity and hirsutism showing significant associations.
7 citations
,
January 2013 in “Ophthalmic plastic and reconstructive surgery” This case report describes a rare instance of late-onset, bilateral nevus comedonicus of the eyelids in a 79-year-old man, highlighting its clinical and histopathologic features.
6 citations
,
January 2001 in “Cambridge University Press eBooks” This review discusses how androgen excess in polycystic ovary syndrome can lead to hirsutism, seborrhea, and worsen conditions like androgenetic alopecia and acne, but includes no new research findings.
6 citations
,
July 1976 in “JAMA” This article discusses dermatological issues associated with black skin, such as postinflammatory pigmentation and keloids, and highlights the need for practitioners to understand these racial characteristics; it reports no new clinical results.
3 citations
,
May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
2 citations
,
February 2019 in “Journal of dermatological treatment” This study introduced a surgical technique involving tweezers to effectively treat acne vulgaris, achieving complete healing in 99% of 4566 patients within up to 50 treatments, potentially reducing psychological distress and medication side effects.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
January 2024 in “MEDS Chinese Medicine” This paper reviews recent progress in clinical research on using acupuncture and moxibustion to treat acne, summarizing the effectiveness of various methods and highlighting advancements over the past five years.
June 2022 in “Indian Dermatology Online Journal” This case report describes a 19-year-old male with alopecia totalis and comedones over the bald scalp, suggesting the importance of terminal hair for sebum drainage to prevent preliminary acne lesions.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used single-cell transcriptomic analysis to identify a specific cell population in acne patients' non-lesional skin, providing evidence for the comedone switch hypothesis by suggesting a shift towards infundibular differentiation at the expense of sebaceous gland maintenance.
May 2024 in “Indian Journal of Dermatology” In this case report, a 22-year-old female was diagnosed with follicular Dowling-Degos disease based on clinical and histological findings, with symptoms including skin lesions confined to hair follicles. The report emphasizes the importance of differentiating this rare variant from similar conditions for proper management.
June 2022 in “Journal of Education, Health and Sport” This article reviews current acne treatments linked to polycystic ovary syndrome in adults but reports no new clinical findings.
January 2022 in “Clinical Cases in Dermatology” This case report describes a middle-aged man with niacinamide-induced poikilodermatous flushing observed on the neck, established through clinical and dermatoscopic evaluation.
This study found that a combination of photoprotector and nighttime formulations with essential oils improved skin barrier function and structural characteristics in young men's oily, acne-prone, and photoaged skin.
July 2019 in “Journal of case reports and scientific images” This article documents a case of acne vulgaris in a 23-year-old female patient and reports no new research findings.
January 2019 in “Springer eBooks” Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
August 2016 in “Journal of evolution of medical and dental sciences” This study describes the clinical profile of acne vulgaris in patients from a tertiary care hospital, noting a male predominance and frequent occurrence of post acne hyperpigmentation.
1 citations
,
October 2020 in “Research Square (Research Square)” This study found that abnormal Wnt signalling in stem cells may contribute to blackhead formation in acne by inhibiting cell differentiation and causing cell accumulation in the junctional zone.
150 citations
,
October 2012 in “Clinical Endocrinology” In this retrospective cohort study, women with polycystic ovary syndrome showed high incidence and age-specific prevalence rates of type 2 diabetes, myocardial infarction, and angina, particularly in those over 65.
4 citations
,
June 2024 in “British Journal of Dermatology” This study found that treatment with EGFR inhibitors or mitogen-activated kinase inhibitors may compromise the immune privilege of human scalp hair follicles, suggesting new directions for managing drug-induced folliculitis.
August 2006 in “JNCI Journal of the National Cancer Institute”