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Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Leflunomide and anthralin may effectively treat severe alopecia areata.

Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.

New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Murine hair has specific types of ceramides and glucosylceramides but lacks acylceramides.

ACBP is crucial for healthy skin in mice.

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

A new non-invasive method can analyze skin mRNA to understand skin diseases better.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

Placental growth factor may help treat hair loss.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Akt2 protein is essential for normal cell division in early mouse embryos.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.