research Queries and Minor Notes: Effectiveness of Prolonged Antisyphilitic Treatment
The reply suggests checking for false positive or asymptomatic syphilis and using penicillin for treatment if necessary.
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60-90 / 1000+ results research Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition
The study investigated the role of polyamines in hair follicle function and fiber composition in sheep. It found that inhibiting ornithine decarboxylase with alpha difluoromethylornithine altered fiber characteristics but did not inhibit wool follicle growth in culture. Conversely, inhibiting S-adenosylmethionine decarboxylase with methylglyoxal (bis)guanylhydrazone completely inhibited fiber growth, which could be reversed by adding spermidine, but not spermine. The study concluded that polyamines, particularly spermidine, were crucial for hair growth, as evidenced by the ability of spermidine to partially counteract growth depression in methionine-deficient conditions.
research New Approaches to the Treatment of Osteoporosis
Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
research Metabolite Screening of Aromatic Amine Hair Dyes Using In Vitro Hepatic Models
The study investigated the potential oxidative metabolism of nine aromatic amine compounds used in hair dyes using human liver microsomes and hepatocytes. Toluene-2,5-diamine (TDA), p-aminophenol, m-aminophenol, p-methylaminophenol, N,N′-bis(2-hydroxyethyl)-p-phenylenediamine, and 1-hydroxyethyl-4,5-diaminopyrazole showed no evidence of oxidative metabolism. While oxidized metabolites of 4-amino-2-hydroxytoluene (AHT), 2-methyl-5-hydroxyethylaminophenol (MHEAP), and phenyl methyl pyrazolone (PMP) were detected, they did not exhibit NADPH-dependent covalent binding, indicating they were not reactive. Further studies in human hepatocytes revealed that all compounds underwent conjugation without forming oxidative metabolites. The findings suggested that the tested hair dye ingredients did not metabolize into potentially reactive oxidized metabolites in the liver.
research Regeneration of a New Hair Follicle from the Upper Half of a Human Hair Follicle in a Nude Mouse
The upper half of a human hair follicle can grow a new hair in a mouse, but success is rare.
research On the Horizon From the ORS: Platelet-Rich Plasma and Bone Health Studies
PRP treatments have shown mixed results for healing, and future research should focus on how PRP is used and which type is used.
research Luxury Hair Fibers for the Fashion Industry
The industry should promote pure luxury hair fibers, improve technology, and diversify products to support growers and ensure sustainable use.
research Ex Vivo Dermatoscopy of Scalp Specimens and Slides
Ex vivo dermatoscopy may lower lab costs and improve diagnosis speed for hair loss biopsies.
research The De Novo DNA Methyltransferase DNMT3A Is Required for Epidermal Homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research The Cochrane Database of Systematic Reviews - Issue 5 2012
The Cochrane Database published its 5000th review in 2012, covering various health topics and updating conclusions based on new research.
research Reporting on Adverse Clinical Events
Certain medications can reduce mortality risk in COPD patients, but others can increase risks of cardiovascular issues, postoperative delirium, and other adverse effects.
research P33: Experimental Advances in Hair Restoration Surgery
Hair transplant surgeries can be improved by preserving follicles in a special solution, and surgeries done at outpatient facilities are more profitable than those at hospitals.
research CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Platelet-Rich Plasma as a Novel Treatment for Lichen Planopillaris
Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.
research Wear Characteristics of Epoxy-Based Hybrid Composites Reinforced with Short Hair Fibers and Glass Micro Spheres
Adding human hair fibers and glass micro-spheres to epoxy improves its wear resistance and strength.
research Allergic Contact Dermatitis to Topical Brimonidine
A man developed an allergic skin reaction after using brimonidine for rosacea.
research Alopecia Areata Associated with Idiopathic Primary Hypophysitis
Autoimmunity can cause both alopecia areata and idiopathic primary hypophysitis.
research Skin Changes During Pregnancy: A Study from Northeast India
Most pregnant women in Northeast India experience normal skin changes, with specific pregnancy-related skin conditions being rare.
research Dermoscopy of Hair and Scalp Disorders (Trichoscopy) in Skin of Color—A Systematic Review by the International Dermoscopy Society Imaging in Skin of Color Task Force
More research is needed to understand hair and scalp disorders in people with skin of color.
research Whole Blood Transcriptome Profiling Identifies Candidate Genes Associated With Alopecia in Male Giant Pandas
Researchers found genes linked to hair loss in male giant pandas.
research Bullous Lesions in Patients with Cutaneous Lupus Erythematosus: A Clinicopathologic Study
Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.
research Standardization of Eclipta Alba by HPTLC, HPLC, and AAS
The research confirmed that certain methods are reliable for standardizing Eclipta alba and ensuring its safety and quality in herbal products.
research Hair Loss (Alopecia) Treatment Using Rosemary Oil, Peppermint Oil, Amla Oil, and Saw Palmetto: A Students’ Survey
Most students believe rosemary oil, peppermint oil, amla oil, and saw palmetto can help with hair loss.
research Standardized Informed Consent Form for Clinicians Administering Platelet-Rich Plasma
A standardized consent form for PRP injections improves patient trust and legal protection.
research Development and Evaluation of Dutasteride Nanoemulgel for Topical Delivery Against Androgenic Alopecia
The new dutasteride gel improves hair growth for treating baldness.
research Evaluation of Sensory Parameters and Tensile Strength on Damaged Hair After Ten Washes With Mintop Shampoo: An In Vitro Study
Mintop shampoo improved hair smoothness, shine, and strength after ten washes.
research Becker Naevus Syndrome Associated With a Mosaic Pathogenic Variant in ACTB
A girl with Becker naevus syndrome has a genetic variant in the ACTB gene related to her symptoms.
research Dengue-Associated Telogen Effluvium Causing Body Dysmorphic Disorder
Dengue fever can cause hair loss that may lead to serious psychological issues like Body Dysmorphic Disorder in young women.
research A Retrospective Study of Frontal Fibrosing Alopecia from North-East India
The study found that Frontal Fibrosing Alopecia in North-East India mainly affects middle-aged women and is often associated with lichen planus pigmentosus.