11 citations
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January 2016 in “Bipolar Disorder” This article reviews the uses, mechanisms, and side effects of valproate in treating bipolar disorder, noting its first-line status for several manic conditions but also highlighting serious risks such as fetal abnormalities.
December 2024 in “Brazilian Journal of Hair Health” In this case study, a 66-year-old woman with hair-related Body Dysmorphic Disorder and newly diagnosed bipolar disorder experienced significant symptom improvement with psychiatric medications, highlighting a unique comorbidity and response to treatment.
October 2022 in “Dermatology practical & conceptual” This study found that bipolar disorder is more prevalent in patients with hidradenitis suppurativa than in those with psoriasis or in control groups.
11 citations
,
February 2007 in “Journal of Child and Adolescent Psychiatric Nursing” This review discusses the challenges of diagnosing and treating pediatric bipolar disorder and highlights the potential benefits of combined psychopharmacological treatments, noting no long-term efficacy from mood stabilizer monotherapy.
12 citations
,
August 2006 in “American Journal of Psychiatry” Topiramate may help improve disruptive behaviors in children with bipolar disorder.
1 citations
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November 2023 in “Brain and behavior” This study found that spironolactone improved cognitive performance in patients with bipolar disorder experiencing manic episodes, but did not significantly affect manic symptoms, recommending further research with larger sample sizes and longer follow-ups.
5 citations
,
January 2016 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” This report discusses that curly hair is a very rare side effect of valproate, a medication used as a mood stabilizer for bipolar disorder, though such drug-induced hair changes are uncommon.
26 citations
,
September 2009 in “Psychosomatics” This case report highlights the importance of recognizing that neuropsychiatric symptoms in adolescents may signal the onset of systemic lupus erythematosus rather than a primary psychiatric disorder.
3 citations
,
November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
April 2025 in “European Psychiatry” This systematic review and meta-analysis found that mood stabilizers used for bipolar disorder, such as lithium, valproate, carbamazepine, and lamotrigine, resulted in varying prevalence of dermatologic side effects, with lamotrigine showing the highest rash incidence, while severe reactions were rare.
January 2023 in “Research Square (Research Square)” This study suggests that measuring cortisol levels in hair may serve as a useful biomarker for assessing mood in individuals with bipolar disorder over recent months.
October 2007 in “European Neuropsychopharmacology”
65 citations
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July 2013 in “International Clinical Psychopharmacology” This review provides an overview of the prevalence and management of side effects of mood-stabilizing drugs in bipolar disorder patients and reports no new clinical results.
This study is designed to explore how circadian rhythms are affected by obesity and mental health conditions, such as schizophrenia and bipolar disorder, using biological and lifestyle data from independently living adults.
101 citations
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May 2014 in “PLOS ONE” This study found that women with polycystic ovary syndrome have an increased risk of developing depressive disorder, anxiety disorder, and sleep disorder compared to those without the syndrome.
5 citations
,
August 2017 in “The Journal of Clinical Psychiatry” In this letter, excessive hair loss due to telogen effluvium was observed as a distressing side effect in the early months of valproate treatment, potentially linked to disruption in biotin metabolism, although the exact mechanism remains unclear.
November 2022 in “Journal of Investigative Dermatology” This study found shared genetic pathways linking acne with multiple mental health disorders and observed a potential causal relationship between acne and increased depression risk.
2 citations
,
January 2017 in “Düşünen Adam” Agomelatine might help stop hair loss caused by valproate.
2 citations
,
January 2007 in “Toxicologie Analytique et Clinique” This case study observed a massive lithium overdose in a 38-year-old woman with bipolar disorder, who survived despite extremely high lithium concentrations through continuous venovenous hemodiafiltration.
1 citations
,
July 2014 in “Current psychiatry” This review discusses the guidelines for using and monitoring mood stabilizers in bipolar disorders, highlighting that only a minority of patients receive guideline-adherent monitoring.
This study found that overlapping concentration imbalances of metals and proteins could provide new insights into the pathophysiological mechanisms of bipolar disorder and schizophrenia, highlighting ongoing oxidative stress and inflammation in both diseases despite treatment.
33 citations
,
September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
3 citations
,
October 2021 in “Brain Sciences” This review hypothesizes that risperidone long-acting injectable may be linked to bullous pemphigoid in a bipolar patient, though current studies report mixed results.
3 citations
,
September 2024 in “Journal of Pre-Clinical and Clinical Research” This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.
October 2004 in “European Neuropsychopharmacology” This article reviews studies on younger men using finasteride for hair loss, finding persistent sexual and nonsexual side effects like erectile dysfunction and depression, and reports lower neurosteroid levels in affected individuals.
January 2015 in “International Journal of Trichology” Lithium can treat bipolar disorder but may cause hair loss and other hair problems.
24 citations
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July 2005 in “Journal of the American Academy of Dermatology” In this case report, the authors suggest that topiramate, used for treating bipolar disorder, may cause trichomegaly, or excessive eyelash growth, in patients.
16 citations
,
March 2006 in “The American journal of psychiatry” This report describes five cases where sudden akathisia occurred in female patients with bipolar disorder after a ziprasidone dose reduction, emphasizing potential unexpected side effects of second-generation antipsychotics.
1 citations
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October 2023 in “Journal of clinical psychopharmacology” In this case report, a young male developed bilateral pleural effusion and persistent fever after starting divalproex sodium for bipolar disorder, which improved upon discontinuation of the drug, suggesting a possible link between divalproex sodium and pleural effusion.
15 citations
,
April 2008 in “Headache” This review discusses the complex relationship between migraine and psychiatric disorders, highlighting the need for individualized treatment plans but reports no new clinical results.