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Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.

A rare biotin deficiency in an Iraqi family caused severe symptoms but was successfully treated with lifelong biotin.

Valproic acid does not change biotinidase enzyme activity in children's blood.

Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Biotin supplements did not significantly reduce hair loss in rats on valproic acid.

Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.

Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.

The drug Albendazole, used for treating parasites, can cause sudden hair loss.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Valproic acid may help hair grow and could be a safe treatment for hair loss.

Valproic acid increases hair count in men with hair loss.

Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Many dermatologists in Saudi Arabia recommend vitamins and minerals for hair loss, often based on personal experience rather than strong evidence.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Certain nutrients can improve skin health and treat skin problems safely.

Biotin supplements for hair improvement are popular without scientific proof of effectiveness.

Valproate can cause hair problems, but there are ways to manage them.

Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.

The conclusion suggests using a science-based, multi-targeted treatment for hair loss instead of just biotin.

Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

The herbal supplement increased hair thickness and reduced scalp oiliness in women.

Some medications, including retinoids, antifungals, and psychotropic drugs, can cause reversible hair loss if stopped or doses are reduced.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.