October 2023 in “International Journal of Cosmetic Science” In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.
5 citations
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August 2017 in “The Journal of Clinical Psychiatry” In this letter, excessive hair loss due to telogen effluvium was observed as a distressing side effect in the early months of valproate treatment, potentially linked to disruption in biotin metabolism, although the exact mechanism remains unclear.
50 citations
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May 1985 in “The journal of pediatrics/The Journal of pediatrics” This study reported successful treatment of biotin deficiency in three patients receiving total parenteral nutrition, suggesting current biotin supplementation recommendations may be inadequate to maintain normal biotin status.
10 citations
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October 2017 in “Pediatric neurology” This case report suggests that poor hair and nail growth in children with autism spectrum disorder and developmental delay may indicate a biotin-responsive condition, as biotin and acetazolamide therapy improved symptoms and school performance in the reported patient.
5 citations
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October 2019 in “Giornale italiano di dermatologia e venereologia” This review highlights the potential benefits of biotin in treating skin disorders related to biotin deficiency but reports no new clinical results.
21 citations
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June 2011 in “Journal of child neurology” This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.
1 citations
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July 2022 in “Dermatologic Therapy” This study found that a 6-week treatment with both brands of biotin and dexpanthenol significantly improved hair fall count and hair density in people with diffuse pattern hair loss, with no significant difference between the two brands.
In this randomized controlled trial, PRP combined with redensyl, saw palmetto, and biotin showed superior efficacy in improving androgenetic alopecia grading scores in male patients when compared to PRP with Procapil.
1 citations
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October 2018 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” In this study, the researchers reported that women with diffuse telogen alopecia who took Wolvit® (biotin 5 mg) daily for 3 months showed a significant decrease in hair in the telogen phase and an increase in hair thickness and growth speed.
August 2026 in “Bulletin of the Medical Institute of Continuing Education” This observational study found that a high-dose biotin regimen of 10,000 mcg/day reduced hair loss and improved hair and scalp conditions in female patients with androgenic alopecia, with effects lasting beyond treatment discontinuation, warranting further investigation into biotin's role in combination therapy.
September 2017 in “BAUST Journal”
82 citations
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August 2017 in “Cell Reports” This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.
11 citations
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May 2009 in “Actas Dermo-Sifiliográficas” This review discusses various therapeutic options for alopecia areata and reports no new clinical results; treatments may manage symptoms but do not cure the condition.
1 citations
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June 2017 in “Journal of The American Academy of Dermatology” PRP treatment for hair loss shows promise, with 58% of patients satisfied and most noticing improvement within 6 months.
This study found that among transgender and gender diverse adults, facial hair is important for gender affirmation but often causes dissatisfaction and financial strain due to inadequate insurance coverage for hair care treatments.
September 2022 in “Polish Hyperbaric Research” This study analyzed 57 medicinal and cosmetic preparations available in Poland for treating alopecia, finding that finasteride is the most common active ingredient, with many products being in tablet or shampoo form and categorized as prescription drugs and cosmetics.
This study conducted a literature review and found that intradermotherapy, a minimally invasive technique involving needle punctures and drugs like minoxidil and finasteride, appears to be safe and effective for short-term treatment of alopecia, with satisfactory results and no significant side effects.
April 2019 in “Journal of the Endocrine Society” This case report suggests that a supplement containing biotin, beta carotene, vitamin C, zinc, and copper may improve insulin resistance markers and hair loss in a patient with non-classic 11-hydroxylase deficiency.
40 citations
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August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
39 citations
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September 2013 in “Journal of Cosmetic Dermatology” This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.
9 citations
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July 2014 in “PubMed” This review examines the scientific evidence behind alternative treatments for female pattern hair loss and androgenetic alopecia, such as biotin, caffeine, and melatonin, but provides no new clinical results.
1 citations
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January 2011 in “The annals of clinical and analytical medicine” This study observed that a mesotherapy formulation was associated with statistically significant improvements in hair quantity, thickness, and scalp condition among 23 patients with androgenetic alopecia, without noted side effects.
In this study, researchers assessed the stability of various formulations in the TrichoConcept™ line for customized alopecia treatment. They found that the combinations remained stable from 14 to 180 days, supporting the use of these vehicles for enhancing therapeutic outcomes in hair loss treatments.
December 2024 in “Фарматека” Oral collagen combined with other treatments effectively reduces hair loss and improves hair quality in telogen effluvium.
September 2021 in “Farmacja Polska” In this summary of needle mesotherapy's role in treating alopecia, the researchers highlight its use in delivering beneficial substances directly to the skin or hair follicles, showing hair loss reduction after one treatment and hair regrowth after several sessions, although contraindications exist for certain populations.
3 citations
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August 2022 in “Molecules/Molecules online/Molecules annual” This study found that microbial adenosine and biotin treatments derived from Staphylococcus epidermidis Cicaria culture may help inhibit hair loss by maintaining the hair's growth phase.
9 citations
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November 2014 in “Journal of Cutaneous Medicine and Surgery” This study found that a majority of dermatologists in Saudi Arabia believe in using vitamins and minerals to treat hair loss but emphasized the need for more research to confirm their effectiveness.
October 2021 in “Interfaces Científicas” This study analyzed the nutritional composition of 75 nutricosmetic products, finding common ingredients like biotin and zinc, but emphasized the need for further research on their effectiveness for hair and nail health.
1 citations
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September 2022 in “JAAD international” This study analyzed social media posts on alopecia areata treatments and found that while most reported perceived improvement, many treatments, particularly dexamethasone, were associated with underlying negative emotions.
January 2023 in “International journal of sciences” This case study reported significant hair regrowth in a 67-year-old woman with telogen effluvium following SARS-CoV-2 infection after treatment with a combination of active agents, laser therapies, and medications.