53 citations,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
50 citations,
May 1985 in “The journal of pediatrics/The Journal of pediatrics” Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.
43 citations,
April 2005 in “The Journal of Dermatology” Biotin supplements improved skin and hair in a biotin-deficient infant on amino acid formula.
29 citations,
July 1996 in “Acta Paediatrica” Biotin should be added to Japanese amino acid formula to prevent deficiency.
27 citations,
July 1946 in “The journal of nutrition/The Journal of nutrition” Biotin and inositol are crucial for pig health and growth.
24 citations,
May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
22 citations,
September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
21 citations,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
13 citations,
August 2020 in “Journal of Laparoendoscopic & Advanced Surgical Techniques” Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
13 citations,
January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
11 citations,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
10 citations,
October 2017 in “Pediatric neurology” Biotin and acetazolamide improved hair and nail growth, mental function, and reduced headaches in a child with autism.
10 citations,
September 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
6 citations,
April 2019 in “Nutrients” Biotin is important for keeping zinc levels balanced in the skin and its lack can cause hair loss.
6 citations,
January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
5 citations,
March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
5 citations,
October 2019 in “Giornale italiano di dermatologia e venereologia” Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.
5 citations,
May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
5 citations,
August 2017 in “The Journal of Clinical Psychiatry” Biotin may effectively treat hair loss caused by valproate medication.
4 citations,
March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
4 citations,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
4 citations,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
2 citations,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
2 citations,
March 2020 in “PubMed” Biotin deficiency is not a major cause of Telogen Effluvium hair loss.
2 citations,
January 2019 in “Elsevier eBooks” Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.
1 citations,
July 2023 in “Plastic and Aesthetic Nursing” Biotin and collagen may improve hair health.
1 citations,
July 2022 in “Dermatologic Therapy” Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.
1 citations,
February 2022 in “Biological Trace Element Research” The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
1 citations,
February 2022 in “Journal of the American Academy of Dermatology” Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.
1 citations,
February 2020 in “PubMed” The topical solution improved hair density and appearance in men with androgenetic alopecia.