research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
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research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Female Pattern Hair Loss: A Review Article
Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2
Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
research Efficacy of Tofacitinib in Treatment of Alopecia Universalis in Two Patients
Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.
research Diagnosis and Management of Alopecia in Children
The guide explains how to identify and treat children's hair loss, including fungal infections, autoimmune disorders, hairstyle changes, self-correcting conditions, and behavioral therapy for hair-pulling.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research Alopecia With Endocrine Therapies in Patients With Cancer
Endocrine therapies for cancer significantly increase the risk of hair loss.
research The Human Skin Microbiome in Selected Cutaneous Diseases
Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
research Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy
The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Promotion of Homology-Directed DNA Repair by Polyamines
Polyamines help fix DNA damage accurately in cells.
research Premature Graying of Hair: Causes, Associations, and Treatments
Premature graying of hair may suggest health issues and currently lacks effective treatments.
research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia
Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal, and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis
α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
research Chemoprevention of Smoke-Induced Alopecia in Mice by Oral Administration of L-Cystine and Vitamin B6
Taking L-cystine and vitamin B6 can prevent hair loss caused by smoke in mice.
research Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
FA2H is essential for normal fur and sebum production in mice.
research Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles
SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
research Dietary Glucoraphanin Prevents the Onset of Psychosis in Adult Offspring After Maternal Immune Activation
Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.
research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Central Centrifugal Cicatricial Alopecia: An Approach to Diagnosis and Management
Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Alopecia and the Metabolic Syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development
BAF200 is essential for proper heart and coronary artery formation.
research Differential Diagnosis of Hair Loss in Children
The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.
research Androgenetic Alopecia: Treatments and Efficacy
Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
research The Cross-Section Trichometer: A New Device for Measuring Hair Quantity, Hair Loss, and Hair Growth
The Cross-section Trichometer is a new tool that can measure hair quantity and detect hair loss and growth.