December 2018 in “Journal of the American Academy of Dermatology” Biotin treatment for hair, nail, and skin disorders has weak evidence and should not be recommended unless new research shows clear benefits.
September 2017 in “Hair transplant forum international” Biotin is popular for hair loss, but there's little scientific proof it works.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
11 citations
,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
5 citations
,
May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
April 2024 in “Journal of the American Academy of Dermatology” Taking biotin supplements for hair and nails may not be helpful and could cause harm.
November 2022 in “Journal of the Endocrine Society” Taking biotin can lead to incorrect low results in free testosterone tests.
82 citations
,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
13 citations
,
August 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
6 citations
,
June 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
4 citations
,
December 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
1 citations
,
July 2022 in “Dermatologic Therapy” Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.
April 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Using both minoxidil and biotin together increased hair growth more than using either one alone.
July 2023 in “Cureus” Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.
March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” The best biotin hair tonic formula has 20% span 80, 9.47% tween 80, and 5% PEG 400.
May 2022 in “International Journal of Biochemistry Research and Review” Plant-based biotin from SesZenBioTM could be twice as effective as synthetic biotin for hair care.
May 2022 in “Endocrine practice” High-dose biotin can cause false thyroid test results; stop taking biotin two days before testing to avoid errors.
September 2021 in “Crop research/Crop Research” Aluminum foil packaging kept the biotin nutrition bar with the least bacteria after 30 days.
January 2021 in “Scandinavian journal of clinical and laboratory investigation” The document describes a way to measure biotin in blood to prevent wrong test results in hormone level testing.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
10 citations
,
October 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
8 citations
,
January 2020 in “Biomaterials Science” Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
4 citations
,
April 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
August 2022 in “Journal of the American Academy of Dermatology” The authors agree they didn't discuss the risks of too much micronutrients and value the focus on biotin deficiency signs and treatment effectiveness.
September 2020 in “Benha Journal of Applied Sciences” Patients with Alopecia Areata have lower levels of zinc and biotin than healthy individuals.
January 2022 in “Journal of Clinical and Diagnostic Research” Using platelet-rich plasma injections and biotin pills together significantly increases hair regrowth in men with hair loss.
2 citations
,
August 2021 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
January 2021 in “Journal of clinical & experimental dermatology research”
May 2023 in “PubMed” Redensyl, saw palmetto, and biotin with platelet-rich plasma is a better treatment for hair loss than Procapil with platelet-rich plasma.