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Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

A blood pressure drug, diltiazem, may also help treat influenza.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Pantethine may boost the immune system's ability to fight sarcoma.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.

The research identified 12 antioxidant compounds in Polygonum multiflorum roots, suggesting these as quality markers for the plant's processed roots.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Some minoxidil combinations can help differentiate leukemia cells without harming other cells.

The peach gene pCTG134 helps control the interaction between auxin and ethylene hormones during fruit ripening.

Pinus densiflora extract may help improve memory and reduce brain inflammation.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Inhibiting ODC can prevent UV-induced skin cancer.

Astaxanthin may improve health by reducing inflammation, stress, and cholesterol, and by enhancing skin health and sports performance.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Nutritional supplements may help improve hair growth in female pattern hair loss.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.