research The Genetic Architecture of Alopecia Areata
Genetic discoveries are leading to new treatments for alopecia areata.
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870-900 / 1000+ resultsresearch Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
research PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells
PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research A Screen for Key Genes and Pathways Involved in High-Quality Brush Hair in the Yangtze River Delta White Goat
Certain genes and pathways are crucial for high-quality brush hair in Yangtze River Delta White Goats.
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat
Researchers found WNT10A to be a key gene in developing goat hair follicles.
research A Counter Gradient of Activin A and Follistatin Instructs the Timing of Hair Cell Differentiation in the Murine Cochlea
Activin A and follistatin control when hair cells develop in mouse ears.
research Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats
The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
research Circulating Testosterone and Feather-Gene Expression of Receptors and Metabolic Enzymes in Relation to Melanin-Based Coloration in the Barn Owl
Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
research Baicalin Inhibits Recruitment of GATA1 to the HSD3B2 Promoter and Reverses Hyperandrogenism of PCOS
Baicalin may help reduce excessive male hormone levels in PCOS.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Alpinetin Promotes Hair Regeneration via Activating Hair Follicle Stem Cells
Alpinetin helps grow hair by turning on hair stem cells and is safe for use.
research Ligand-Independent Actions of the Vitamin D Receptor: More Questions Than Answers
The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
research The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus
Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
research Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats
Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.
research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.
research Long-Term Administration of Triterpenoids From Ganoderma Lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus
Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research New Insights Into Human Hair: SAXS, SEM, TEM, and EDX for Alopecia Areata Investigations
Alopecia Areata causes significant structural and compositional changes in hair.
research Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape
The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
research Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA
Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
research Analysis of Genome DNA Methylation at Inherited Coat Color Dilutions of Rex Rabbits
Inherited color dilution in rabbits is linked to DNA methylation changes.
research Polycystic Ovary Syndrome and Oxidative Stress: From Bench to Bedside
Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
research Drivers of Plateau Adaptability in Cashmere Goats Revealed by Genomic and Transcriptomic Analyses
The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.
research Evaluation of Serum Levels of IL-6, IL-10, and TNF-a in Alopecia Areata Patients: A Systematic Review and Meta-Analysis
Alopecia areata patients have higher levels of IL-6 and TNF-α.
research The Beneficial Effects of Chick Embryo Extract Preconditioning on Hair Follicle Stem Cells: A Promising Strategy to Generate Schwann Cells
Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.