June 2026 in “Journal of Investigative Dermatology” This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.
June 2026 in “Dermatology and Therapy” This review provides an analysis of topical treatments with clinically proven efficacy for managing hyperpigmentation and concludes that the most effective approach is using combined therapies that target multiple aspects of skin pigmentation physiology.
January 2025 in “International Research Journal of Innovations in Engineering and Technology” This review discusses the biological mechanisms, preparation techniques, and clinical applications of platelet-rich plasma therapy, highlighting its variable outcomes and potential improvements for efficacy and standardization; it reports no new clinical results.
2 citations
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April 2025 in “Biologics” This study reviewed clinical trials and reports on cytokine-targeting biologics for alopecia areata, finding Dupilumab and Ustekinumab showed strong efficacy, while other biologics had limited success or worsened the condition. Further research is needed to optimize biologic therapies for AA.
53 citations
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January 1993 in “Biochemical Pharmacology” This study reports a method for efficiently synthesizing chromeno-pyrimidine-N-oxides in good to excellent yields, confirmed by X-ray analysis, through a reaction between 4-chloro-3-formylcoumarin and aromatic carboximide oximes.
7 citations
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November 2022 in “Communications biology” This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.
12 citations
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September 2022 in “Frontiers in Genetics” This study identified seven genes that may serve as biomarkers for diagnosing skin cutaneous melanoma by analyzing the relationship between UV exposure, ferroptosis, and the cancer's pathology.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review summarizes current clinical evidence on platelet-rich plasma, highlighting its effectiveness in treating androgenetic alopecia and as an adjunctive therapy for acne scars, while noting challenges in standardizing preparation techniques.
February 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses the current evidence on platelet-rich plasma therapy's biological mechanisms and clinical applications, highlighting its promise in regenerative medicine and the challenges to its integration in nursing practice.
December 2024 in “Journal of Education Health and Sport” This study explored how excessive sugar consumption detrimentally affects skin health by promoting processes like glycation and inflammation, concluding that a low-glycemic index diet could help prevent and manage skin conditions such as acne and psoriasis.
47 citations
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March 2017 in “Materials Science and Engineering: C” In this study, decellularized human amniotic membrane was found to promote wound healing and reduce scar formation in rats with full-thickness skin defects, compared to traditional clinical treatments.
December 2022 in “Communications biology”
December 2022 in “Communications biology”
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” This study systematically reviews the Wnt/β-catenin signaling pathway, discussing its origin, composition, function, involvement in tumors and diseases, and the development of small-molecular compounds targeting this pathway for disease treatment.
December 2025 in “Dietetics” This paper reviewed studies from 2019 to 2025 on the use of olive oil and other derivatives from the European olive tree for skin, hair, and nail care, noting their roles in wound healing and skin aging while highlighting a favorable safety profile.
November 2010 in “Bradford Scholars (University of Bradford)” In this study, the authors reported that NNC55-9216, a selective SUR1 KATP channel opener, stimulated hair follicle growth in culture and enhanced the effects of minoxidil, suggesting a new potential treatment for hair loss.
September 2026 in “Cureus” In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.
January 2025 in “Stem Cells International” In this review, researchers discuss the role of epigenetic modifications in epidermal stem cells' decline during skin aging and identify potential interventions targeting these disruptions, suggesting significant possibilities for antiaging strategies and dermatological treatments.
June 2025 in “Stem Cell Research & Therapy” This review highlights recent advancements in androgenetic alopecia treatment, focusing on the dysregulated signaling pathways involved in hair follicle regeneration and exploring innovative therapeutic strategies, including small molecule modulators and gene editing technologies, which show promise in preclinical models.
This review explores plant-derived exosomes as promising alternatives to synthetic wound-healing agents due to their ability to regulate signaling pathways involved in skin repair, while also addressing challenges in their clinical application.
January 2023 in “Advances in pharmacology and clinical trials” This review highlights that human hair is a valuable biological matrix for clinical and toxicological analyses, demonstrating its applicability in detecting various active substances from different pharmacological classes.
68 citations
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May 2024 in “International Journal of Molecular Sciences” This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.
January 2024 in “International Journal of Applied Research” In this cross-sectional study on Iraqis, 74.5% of participants self-reported hair loss following COVID-19 infection, with the highest prevalence among those aged 19-29, pointing to a potential link between COVID-19 and increased risk of telogen effluvium.
February 2017 in “Cancer Causes & Control” In this study, Swedish men carrying the AR haplotype H2 were found to have a significantly lower risk of prostate cancer compared to those with the more common H1 variant.
Targeting a specific lipid could help treat male pattern baldness.
27 citations
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August 2014 in “Wiley interdisciplinary reviews. Developmental biology” This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.
5 citations
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May 2024 in “BMC Genomics” This study analyzed the transcriptome of the Tianzhu white yak, identifying differential transcripts that shed light on the molecular mechanisms influencing hair length growth variation in this species.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
18 citations
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April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores the potential genetic and epigenetic influences on hair whorl patterns and suggests that pattern formation may involve basic physical-chemical laws, although it reports no new experimental findings.
January 2005 in “Korean Journal of Psychosomatic Medicine” This study found that females with chronic alopecia, including both alopecia areata and androgenetic alopecia, experienced higher levels of depression, anxiety, and alexithymia than healthy controls.