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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Polymeric nanoparticles show promise for treating skin diseases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

PGD2 stops hair growth and is higher in bald men with AGA.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Researchers created human hair follicles using a new method that could help treat hair loss.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Use minoxidil for hair loss treatment; assess results after 6 months.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.