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This review explores advancements in cytokine engineering for regenerative medicine, highlighting the development of modified cytokines with enhanced stability and tissue-targeting, potentially improving treatments for chronic wounds and fibrotic diseases by promoting tissue healing and minimizing inflammation, while adapting concepts from cancer immunotherapy.

This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.

This study introduces a magnet-assisted fabrication strategy for creating complex 3D soft bioscaffolds, demonstrating its effectiveness by producing structures with overhangs and supporting biohybrid actuators, promising advancements in biomedical applications.

This review discusses the current techniques for engineering microtissues, emphasizing the potential of continuous microfluidic processes to facilitate large-scale production, but reports no new experimental results.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This review introduces a framework to integrate bioinspired conductive materials and advanced 3D/4D printing in regenerative medicine for dynamic, responsive tissue regeneration, emphasizing the potential of smart scaffolds to adapt to physiological cues.

This review highlights the transformative potential of bioinspired polymers in biomedical engineering, focusing on their roles in enhancing tissue engineering, regenerative medicine, and other biomedical applications, with innovations including mimicking the extracellular matrix, self-healing, antibacterial properties, and cancer therapy.

This study found that heart-inspired hollow hydrogel-based scaffolds enhanced regenerative capability in osteoporotic bone defects and increased cell number when using a mechanical-assisted post-bioprinting strategy.

This mini-review reports that advances in microbioreactor technology, particularly with microfluidics, significantly enhance eukaryotic cell-based biomedicine by improving productivity, scalability, and reproducibility in applications like CAR T-cell manufacturing and organoid growth, though challenges in scalability and material selection remain.

This review discusses the various components essential for successful tissue engineering, such as cell sources, modification methods, and supportive matrices, and highlights the need for functional synergy without reporting new experimental results.

This study demonstrated that a mechanical-assisted post-bioprinting strategy significantly increased cell numbers and enhanced regenerative capabilities in hollow hydrogel-based scaffolds for bone defect repair in vivo.

This overview outlines the latest advancements and challenges in developing three-dimensional scaffolds for biomanufacturing cultured meat, focusing on organizing muscle stem cells to better mimic the structure of traditional meat. Results are not reported in the abstract.

This study introduces a new multiaxial bioreactor system that uniformly stretches tissue-engineered skin grafts and improves skin tissue maturation through enhanced cellular distribution and environmental monitoring.

This study introduces a new type of tissue micromodule, the micro tissue precursor (μTP), which can form complex 3D tissues, including lung stroma and skin models supporting hair viability.

This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.

This review outlines various 3D bioprinting techniques and bioinks used for creating artificial tissues and organs, emphasizing their potential in addressing organ transplant shortages and advancing drug testing, while acknowledging existing challenges and future prospects.

This narrative review reports that tissue-engineered scaffolds for wound healing generally match standard care outcomes, with some trials indicating faster healing and improved scar quality, despite challenges like limited cellular infiltration and inadequate vascularization.

This chapter describes methods for creating engineered skin substitutes with chimeric hair follicles using human and murine cell grafts in immunodeficient mice, but reports no clinical outcomes.

This study found that combining hair follicle-derived smooth muscle cells with a natural biomaterial created vascular constructs with mechanical and functional properties similar to native arteries, suggesting potential for arterial implantation.

In this study, tubular 3D bioprinted structures made from sodium alginate and gelatin, containing NIH/3T3 fibroblast cells, demonstrated the ability for cell growth and network formation over 6 weeks, although structural tensile strength decreased with cell growth and polymer degradation.

This review highlights how engineered hydrogels can modulate immune niches and serve as in vivo models to study them, noting collaboration is needed to advance therapeutic outcomes.

This review explores biomaterials in non-viral gene delivery systems and highlights the need for more research to better understand how various parameters affect gene delivery processes, without reporting new experimental results.

This review examines the design and applications of DNA hydrogels in regenerative medicine, discussing their potential for tissue repair in areas like bone and skin, and their role in tumor therapy, while providing insights into their molecular design and construction strategies.

This study discusses the challenges in translating organoid models from laboratory settings to clinical and commercial applications, emphasizing the need for engineering approaches like environmental recapitulation and matrix engineering to bridge this gap.

In this study, probiotic-functionalized nanocomposite scaffolds accelerated wound healing and inhibited harmful bacteria in burn wounds on mice, suggesting a potential new approach for infection control and healing promotion.

This review discusses the biofunctionalization of hydrogel scaffolds for vascular tissue regeneration and reports promising results from in vivo studies, such as improved angiogenesis and healing in pressure ulcers when using specific peptides.

This review discusses the principles, materials, and applications of melt electrowriting-based 4D printing for creating biomimetic scaffolds, but reports no new clinical results; it highlights recent advancements and remaining challenges in the field.

This review discusses strategies and advances in bioprinting for skin wound healing, concluding that bioprinting could offer promising solutions for skin regeneration despite existing challenges.