June 2024 in “BioSCIENCE” This study reviewed the use of microinfusion of microparticles (MMP®) with methotrexate for treating alopecia frontal fibrosante and found it reduced symptoms associated with the condition and improved specific scalp measurements, showing that the technique is safe and well-tolerated.
April 2024 in “Más dermatología” This study reported that bioactive peptides from skin collagen, obtained through selective hydrolysis, improve skin collagen synthesis and remodeling, while inhibiting its breakdown by metalloproteinases, showing benefits such as enhanced skin hydration, elasticity, healing, and hair restoration, without associated adverse effects.
In this integrative review, researchers assessed the efficacy of oral minoxidil for treating alopecia, finding that it appears effective, especially for female androgenetic alopecia, though evidence quality is very low and side effects limit its use compared to topical forms.
January 2024 in “La Ciencia al Servicio de la Salud y Nutrición” This narrative review attributes antiandrogenic properties to spironolactone, reporting its effectiveness in treating dermatological conditions like alopecia androgenica, acne, and hirsutism, though highlighting necessary attention to potential adverse effects and contraindications.
In this study, low-dose oral minoxidil was found to have a favorable safety profile for treating alopecia, with mostly mild side effects, in both general and hypertensive populations.
November 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and education.
October 2023 in “Open Repository of the University of Porto (University of Porto)” In this study, a pharmacy internship report describes a six-month community pharmacy internship, detailing activities to promote sleep quality, sun protection, hypertension screening, and detecting medication errors, as well as in-depth discussions on smoking cessation and alopecia treatments.
January 2023 in “Brazilian Journals Editora eBooks” Girls with Autism Spectrum Disorder may show different symptoms than boys, leading to missed or delayed diagnoses.
January 2023 in “Brazilian Journals Editora eBooks” People with cleft lip and palate often have respiratory problems.
January 2023 in “Brazilian Journals Editora eBooks” Passiflora incarnata may help with anxiety and sleep issues but has side effects; teleconsultation for heart failure can improve quality of life; increased screen time for children during the pandemic led to more clinical complaints; older and severely affected COVID-19 patients are more likely to have long-term symptoms.
January 2023 in “Brazilian Journals Editora eBooks” Nursing staff's mental health was affected during the COVID-19 pandemic.
January 2023 in “Brazilian Journals Editora eBooks” The document concludes that Passiflora incarnata could help with anxiety, telemedicine might improve heart failure care, screen time for kids has increased, pregnant teens in Brazil are mostly okay with their body image, rare tuberculosis infection can occur after knee surgery, older and severely ill people are more likely to have long COVID-19 symptoms, HPLC might diagnose more diabetes cases, and psychiatrists should be involved in pain management.
January 2023 in “Brazilian Journals Editora eBooks” Pharmacists play a key role in managing the use of anxiety medications and ensuring patients use them correctly.
January 2023 in “Brazilian Journals Editora eBooks” Psychiatrists are crucial in pain management teams because they help treat severe pain and related mental health issues.
January 2023 in “Brazilian Journals Editora eBooks” The document concludes that Passiflora incarnata may help with anxiety, healthcare workers need mental support, common bacteria cause hospital UTIs, telehealth for heart failure needs research, kids' screen time has increased, pregnant teens are mostly okay with their body image, diagnosing post-surgery tuberculosis is hard, older and severely ill people are more likely to have long COVID symptoms, and psychiatrists should be part of pain management teams.
January 2023 in “Brazilian Journals Editora eBooks” Surgery to fix a broken upper arm bone can sometimes lead to nerve damage.
January 2023 in “Brazilian Journals Editora eBooks” Passiflora incarnata may help with anxiety but has risks and drug interactions.
There's a genetic link between Fragile X Syndrome and Autism Spectrum Disorder.
6.7% of urine cultures showed hospital-acquired urinary tract infections.
Children used screens more during COVID-19, causing various health complaints.
Autism Spectrum Disorder is often underdiagnosed in females.
Dissociative disorders in childhood sexual abuse victims are more common in males.
Most pregnant teenagers are not dissatisfied with their body image but worry about weight.
Diagnosing tuberculosis after knee surgery is challenging due to non-specific symptoms.
Post-COVID-19 syndrome is more common in older, severely affected patients.
Psychiatrists should be part of pain management teams due to the psychological aspects of pain.
January 2023 in “Brazilian Journals Editora eBooks” HPLC may detect prediabetes and diabetes earlier than Immunoturbidimetry because it shows higher A1c levels.
This study found that while iron depletion through phlebotomies is safe for women with functional ovarian hyperandrogenism, it does not improve their cardio-metabolic profile and may reduce non-enzymatic antioxidant capacity.
This review critically analyzes recent literature on the use of nanotechnology in alopecia treatment, reporting promising results for improving drug delivery and hair growth, though challenges in maintaining physical stability may limit large-scale commercialization.
February 2022 in “Programa de Iniciação Científica - PIC/UniCEUB - Relatórios de Pesquisa” This study found that PRP treatment showed better results than injectable minoxidil for reducing hair loss and promoting hair growth, with noticeable effects after the second application.
This study found that a combination of photoprotector and nighttime formulations with essential oils improved skin barrier function and structural characteristics in young men's oily, acne-prone, and photoaged skin.
This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.
This article discusses vaccination coverage for BCG, Polio, and Hepatitis B in Juiz de Fora using SUS data and reports no new results; the authors aim to hypothesize reasons for coverage variation.
February 1994 in “Neuroscience letters” This review provides an overview of biotin's role in metabolism and the consequences of deficiency but reports no new clinical findings; it highlights that intestinal bacteria usually meet biotin needs.
September 1989 in “Neuroscience letters” This review discusses the role of biotin in metabolism and its dietary requirements, but provides no new experimental findings.
March 1993 in “Neuroscience letters” This summary outlines the essential roles and recommended daily intakes of biotin, while discussing consequences and mechanisms of deficiency, but presents no new research findings.
36 citations
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June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
5 citations
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January 1997 in “PubMed” This study found that finasteride was rapidly absorbed and extensively metabolized in dogs, with most metabolites excreted in feces, and suggests that higher doses might saturate the metabolism mechanism.
55 citations
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September 2017 in “Expert Opinion on Drug Discovery” This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.