September 2021 in “Crop research/Crop Research” This study reported that a biotin-rich nutrition bar stored in aluminum foil packaging showed reduced bacterial growth and remained edible for 30 days compared to other packaging materials.
85 citations
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July 2025 in “Nature Communications” This review examines the evolving field of nanozymes, highlighting their unique properties and biocatalytic capabilities that challenge traditional concepts of biocatalysis, with implications for sustainable applications and potential roles in physiological processes and disease pathogenesis.
May 2026 in “International Journal of Scientific Research in Chemistry” This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.
2 citations
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January 1997 in “Principles of Medical Biology” This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.
January 2002 in “中国人民解放军军医大学学报(英文版)” This study found that human hair keratin scaffold material implanted in damaged rabbit muscle tissue degrades via the ubiquitin system and is further processed by macrophagocytes and lysosomes.
May 2026 in “Nature Communications” In this study, a self-adaptive nanozyme embedded in a madecassoside-enriched hydrogel demonstrated strong antibacterial efficacy and accelerated healing in wounds infected with drug-resistant bacteria, as evidenced by improved repair and regeneration in MRSA-infected mice and preclinical pig models.
11 citations
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January 2006 in “Journal of the American Leather Chemists Association” This study investigated multiple alkaline oxidative dehairing systems and found a consistent reaction mechanism for disulfide cleavage across systems, enhancing hair solubilization by enabling structural swelling and water uptake.
This study demonstrated that de novo designed bifunctional proteins can target and degrade BCL-xL, leading to cell apoptosis, suggesting a new approach to targeted protein degradation therapy.
April 2026 in “Biomolecules” In this study, researchers synthesized biomedical polyurethanes incorporating curcumin and varying PEG content to enhance water solubility and control curcumin release, finding that higher PEG content improved hydrophilicity, swelling, and degradation, while maintaining excellent antioxidant and antibacterial activities, suggesting promise for biomedical applications.
49 citations
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April 2017 in “AFRICAN JOURNAL OF BIOTECHNOLOGY” In this study, the authors explore the use of endophytic fungi as biofactories for producing eco-friendly silver nanoparticles, emphasizing their antimicrobial potential and the methods for their synthesis and analysis in nanobiotechnology.
April 2026 in “International Journal of Drug Delivery Technology” This study discusses advancements in nanotechnology and theranostic dressings, which may significantly improve chronic wound care by effectively targeting biofilms and enabling real-time monitoring, although obstacles to broad applicability and sustainability remain.
8 citations
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October 2013 in “Chemistry Central Journal” This study found that microbial transformation of dihydrotestosterone with two types of fungi produced eight metabolites, among which metabolites 5–7 were significant inhibitors of butyrylcholinesterase, suggesting potential in Alzheimer's disease management.
May 2025 in “Afyon Kocatepe University Journal of Sciences and Engineering” The researchers monitored various pollutants in real cosmetics industry wastewater and reported high removal efficiencies for parameters like Chemical Oxygen Demand and heavy metals through coagulation-flocculation, yet suggested that more effective COD treatment alternatives are necessary to better protect the environment and human health.
34 citations
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April 2012 in “Molecular Biology Reports” This study isolated a thermophilic bacterial strain, Bacillus cereus, from soil that produces an extracellular protease; the enzyme effectively removed non-leather structures from animal pelts and was compatible with commercial detergents.
6 citations
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September 2024 in “Metabolism and Target Organ Damage” This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.
April 2017 in “DR-NTU (Nanyang Technological University)” This study found that adjusting the polymer gel composition can create a more consistent release profile of finasteride with reduced initial burst release, enhancing patient compliance through in situ polymer precipitation.
7 citations
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January 2023 in “Journal of Hematology & Oncology” This review discusses how targeting protein degradation processes may help overcome cancer drug resistance, but reports no new clinical results and suggests further research for precise therapeutic strategies.
1 citations
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May 2025 in “Biomolecules” This study examined the latest advances in synthetic biology for increasing microbial production of sesquiterpenol compounds, highlighting innovative strategies to overcome challenges such as low yields and terpenoid-related toxicity, which hinder industrial-scale applications.
This study found that hair cosmetics have strong bacteriostatic properties, suggesting that current microbial test methods for these products should be revised.
3 citations
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May 2024 in “Biomimetics” This narrative review examines the structure-function relationship in bioactive biopolymers used to promote healing in chronic wounds, emphasizing diabetic ulcers, and underscores the importance of characterizing these biopolymers to enhance their bioactivity for better tissue regeneration outcomes.
January 2024 in “Biotechnology advances” This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.
3 citations
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January 2007 in “Journal of health science” This study found that an enzymatic method effectively identified chemical treatments like perming and dyeing by detecting higher degradation in treated hair compared to untreated hair.
This review describes deep eutectic solvents as a green alternative to toxic solvents in extracting bioactive compounds, highlighting their sustainability, production from natural ingredients, and beneficial properties for pharmaceutical applications.
1 citations
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August 2024 in “Polymers” This review discusses recent advances in protein immobilization on bacterial cellulose for various biomedical uses and reports no new clinical results.
9 citations
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March 2022 in “Journal of Chemical Information and Modeling” This study identified a series of novel β-glucuronidase inhibitors that may help mitigate adverse effects of first-line anti-cancer drugs by targeting gut bacteria, based on virtual high-throughput screening findings.
July 2020 in “Environmental Science and Pollution Research” This study found that finasteride and melengestrol acetate exhibit varying levels of toxicity to freshwater mussels, amphipods, and mayflies, but current environmental concentrations suggest minimal direct effects on these aquatic invertebrates.
This research presentation explored the roles of mammalian multi-copper ferroxidases in iron homeostasis and highlighted new insights into their functions, including non-iron-related ones, while discussing arsenic's role in microbial warfare as a potential antibiotic.
May 2020 in “International Journal of Engineering Applied Sciences and Technology” This study explored the antimicrobial potential of natural bioactive materials such as Citrus lemon, Garlic, Baeckea frutescens, Neem, and Eclipta Alba, highlighting their eco-friendly and non-toxic properties for combating harmful bacteria.
January 2026 in “International Journal of Biomedical Investigation” This review reported that green-synthesized metallic nanoparticles from agricultural waste hold promise for improving chronic wound care due to their antimicrobial, antioxidant, and regenerative properties, though challenges like biosafety and manufacturing scale need addressing for clinical use.
May 2023 in “Indian journal of dermatology, venereology, and leprology” This article aims to enumerate and describe the types of tissue degeneration observed in various dermatopathological conditions, offering beneficial insights for residents studying the deterioration of skin tissues due to inflammatory, infective, drug-induced, or neoplastic stimuli.