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The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Androgens can cause hair growth in some areas but hair loss on the scalp.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

PCOS is a common hormonal disorder in women, often involving menstrual issues and increased diabetes risk, managed through lifestyle changes and targeted treatments.

Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.

Scientists made a sensor that can detect a specific type of RNA related to androgen receptors quickly and accurately.

Pregnancy can trigger follicular mucinosis, which may resolve after delivery.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

Combining proper shaving, topical treatments, and laser therapy effectively reduces Pseudofolliculitis Barbae.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Low ferritin levels are linked to increased hair loss; no link found between vitamin B12, TSH levels, and hair loss.

Melatonin and Lissotriton improved hair quality and increased activity in mice.

Effective PCOS treatments require targeting specific signaling pathways.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.

Hutchinson-Gilford Progeria Syndrome causes rapid aging from a genetic mutation, with no cure but ongoing research into potential treatments.

Zolpidem shows up in hair from the top back of the head after one dose and fades over time, suggesting it gets into hair through blood and sweat.

Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.

Early diagnosis and treatment of PCOS can prevent complications and improve symptoms.