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The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Antiandrogen therapy may help treat hidradenitis suppurativa.

Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Herbal treatments can help manage PCOS symptoms.

Inositol shows promise in treating PCOS and other health issues, but more research is needed.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.

Medications for PCOS don't seem to raise heart disease risk.

Bald men may have higher heart disease risk.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

Using old drugs for new uses can help treat rare immune deficiencies.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Iron deficiency may contribute to hair loss.

New therapies are being developed that target integrin pathways to treat various diseases.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

A rare fungal infection on a child's scalp was successfully treated with antifungal medication.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

The surgery effectively promoted and maintained weight loss in obese women during the first year.