54 citations,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
36 citations,
February 2011 in “Fertility and Sterility” Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
26 citations,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
24 citations,
July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
22 citations,
April 2006 in “Journal of The American Academy of Dermatology” More research is needed to determine if iron deficiency causes hair loss.
21 citations,
January 2005 in “Pediatric Dermatology” An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
20 citations,
March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
19 citations,
December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.
16 citations,
February 2016 in “Gynecological Endocrinology” Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
16 citations,
January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
15 citations,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
10 citations,
January 2013 in “Journal of skin cancer” PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.
9 citations,
July 2011 in “The Journal of Sexual Medicine” Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
4 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.
4 citations,
October 2013 in “Clinics in Dermatology” Experts don't fully agree on how to diagnose certain hair growth disorders and more research is needed to understand them better.
3 citations,
August 2012 in “Nature Cell Biology” Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
1 citations,
January 2009 in “Elsevier eBooks” The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
Iron deficiency anemia can cause itching, which often improves with iron supplements.
December 2021 in “International Journal of Biomedicine” Hyperprolactinemia should be treated before confirming a PCOS diagnosis.
July 2021 in “Research Square (Research Square)” Semecarpus anacardium leaf extract fights breast cancer and extends survival in mice.
August 2012 in “Nature Cell Biology” A pathway helps maintain long telomeres in both stem and cancer cells.
January 2021 in “Menoufia Medical Journal” Women with pattern hair loss often have higher blood sugar, cholesterol, blood pressure, and waist size, suggesting a link between hair loss and metabolic syndrome.
March 2020 in “Journal of evolution of medical and dental sciences” Male pattern baldness, especially the vertex type, could be an early sign of cardiovascular risk factors like high cholesterol and diabetes.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
431 citations,
October 2008 in “Current Medicinal Chemistry” Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
185 citations,
August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
165 citations,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
139 citations,
August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
103 citations,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.