4 citations
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April 2022 in “Microorganisms” In this study, clinically used preoperative skin preparations with povidone iodine and chlorhexidine gluconate did not meet FDA log-reduction standards for bacterial bioburden in a porcine model, suggesting persistent infection risks.
June 2014 in “Wound Medicine” This review discusses evaluation and treatment options for polycystic ovary syndrome and reports no new clinical results; it emphasizes a multi-system approach using the mnemonic "MY PCOS.
40 citations
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August 2014 in “Journal of Nanoparticle Research” This study found that biologically synthesized silver nanoparticle gel demonstrated excellent wound healing efficacy in rats, surpassing both marketed formulations and ionic silver.
21 citations
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February 2015 in “Journal of Feline Medicine and Surgery” This study found that negative pressure wound therapy combined with skin grafting is a feasible method for treating soft tissue and skin defects in cats, achieving a high graft take rate and satisfactory outcomes.
1 citations
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May 2025 in “Natural Products and Bioprospecting” In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.
262 citations
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May 2017 in “Nanomedicine” This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
106 citations
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July 2013 in “Advances in wound care” This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.
24 citations
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June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.
8 citations
,
October 2022 in “Cold Spring Harbor perspectives in biology” The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
1 citations
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July 2019 in “Journal of the Dermatology Nurses' Association” This article discusses highlights from the 2019 Dermatology Nurses' Association's annual meeting, covering various dermatological conditions and treatments, and reports no new clinical findings.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study found that cold atmospheric plasma can accelerate wound healing processes and reduce bacterial growth, including drug-resistant strains, suggesting its potential as a novel treatment for chronic wounds.
April 2026 in “Frontiers in Bioengineering and Biotechnology” This study found that a cellulose membrane significantly shortened the healing time and reduced the ulcer area in patients with chronic venous leg ulcers compared to a standard antimicrobial dressing.
November 2025 in “Nanoscale Advances” This review highlights the potential of inorganic nanoparticle-based scaffolds as innovative tools for advanced wound care, emphasizing their ability to provide antimicrobial action and regenerative support, while also discussing fabrication strategies and challenges in optimizing their clinical application.
April 2024 in “Frontiers in cellular and infection microbiology” This review highlights evidence supporting the potential of blue light therapy as a non-invasive treatment for managing skin and hair conditions by modulating interactions between the skin microbiome and its host.
November 2023 in “Burns and trauma” This review discusses how the skin microbiome impacts different types of cutaneous wounds, such as acute and chronic, and explores therapeutic strategies targeting the microbiome to enhance healing outcomes.
July 2023 in “Institutional Repositories DataBase (IRDB)” Malassezia species may contribute to hair loss in AGA patients.
April 2019 in “Journal of Investigative Dermatology” In this study, researchers found that canonical Wnt/β-catenin signaling and Wnt-ligand expression are distinctly regulated during wound healing across different cell populations and immunity conditions, particularly under type 2 immunity.
April 2019 in “Journal of Investigative Dermatology” This study found that activating the Sonic hedgehog pathway in scarring wounds can redirect wound repair to favor hair follicle regeneration instead of fibrosis.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
This review discusses advancements in regenerative medicine for hair loss treatments, highlighting stem cell techniques for rejuvenating or creating hair follicles, but provides no new clinical results.
January 2018 in “Stem cells in clinical applications” This review discusses the potential of exosomes and the secretome in stem cell-based regenerative therapies but reports no new experimental findings.
August 2017 in “Journal of Pharmacy Practice and Research” This study details a method for assessing the risk of modifications to pharmaceutical frame formulations by assigning a risk priority number using Failure Modes Effects Analysis, which estimates the severity and probability of changes impacting the formulation.
150 citations
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February 2013 in “Surgical Infections” This review discusses the historical and modern use of silver for reducing infections and aiding healing in burns, wounds, and medical devices, noting its benefits and limitations in various applications.
34 citations
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December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
26 citations
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September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.
15 citations
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January 2017 in “Experimental Neurology” This study found that finasteride significantly reduced levodopa-induced dyskinesia in both male and female rats without diminishing l-DOPA's motor benefits, indicating potential for clinical trials in Parkinson's patients.
8 citations
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July 2024 in “PLoS ONE” In a comparative genomic study, researchers observed significant genetic differences among the three chemical races of the alga Botryococcus braunii, leading them to propose reclassifying these races as distinct species based on their unique genomic characteristics.
October 2020 in “Veterinary Dermatology” This review discusses autoimmune blistering diseases across species and highlights new treatment efficacy findings and ongoing trials, but it reports no new clinical results.