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This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.

This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.

In this study, a new formulation of human placental extract showed antioxidant and neurite outgrowth activities, significantly reduced hair graying in mice, and alleviated neuropathy symptoms, suggesting potential therapeutic benefits.

This study found that human placental extract significantly improved melasma, chronic ulcers, and alopecia areata without major adverse effects, suggesting its effectiveness and safety for these conditions.

This study found that human placenta extract may be a promising pulp-capping material, causing less intense chronic inflammation and thicker dentine bridge formation compared to mineral trioxide aggregate in dogs' teeth.

In this study, human placenta extract was observed to enhance the hair-growth-promoting effects of minoxidil and stimulate earlier and prolonged anagen phases in a mouse model.

In this double-blind, randomized controlled trial, researchers found that cow placenta extract lotion was as effective as topical minoxidil 2% in increasing hair count for women with androgenetic alopecia over six months, though the mean increases in hair count were similar for both treatments.

This review outlines the biological effects of various placental extracts, noting their reported antioxidant, anti-inflammatory, and immunomodulatory activities, but highlights that the relationship between these effects and the extracts' specific contents remains unclear.

This study found that human placenta extract may enhance hair growth by increasing PG-E2 and PG-F2a production while decreasing PG-D2 levels in cultured hair follicle keratinocytes.

This study found that cow placenta extract increased hair follicle size and hair length in mice but was less effective than minoxidil, suggesting potential with further refinement.

In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.

This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.

This study found that porcine-placenta-extract-loaded nanoformulated serum improved skin hydration and promoted hair growth, as well as reduced intracellular ROS and inflammation without cytotoxicity in human subjects.

This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.

In this study, the researchers developed a novasome vesicle carrying bovine placenta extract, which demonstrated superior hair growth effects in rats compared to traditional minoxidil and PE-loaded liposomes, and showed good stability and physical characteristics over 90 days at 4°C.

This study suggests that IGF-1, a component of human placenta hydrolysate, promotes hair growth by increasing the number and size of hair follicles in mice.

This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.

This research reported that KDML105 bran extract demonstrated antioxidant activities, reduced nitric oxide production, and influenced gene expression related to the hair cycle in cultured dermal papilla cells, suggesting potential as an anti-hair loss agent by supporting the anagen phase and angiogenesis.

Plant extracts might help control stem cell growth for medical use.

This study suggests that silver nanoparticles synthesized using Grewia optiva leaf extract exhibit stronger antibacterial and antioxidant properties than the leaf extract alone.

This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.

This review highlights the potential of cell-free therapies, particularly cell extracts, in addressing radiation-induced salivary gland damage from head and neck cancer treatment, emphasizing their practicality and safety compared to traditional therapies despite incomplete understanding of their bioactive components.

This study identified a new lignan and 21 known compounds from Asiasarum heterotropoides roots, with two compounds showing potential anticancer activity by influencing NO production, FOXP3 expression, and HIF-1α activity in vitro.

In this study, topical application of Hominis Placenta significantly promoted hair regrowth and increased hair density in C57BL/6 mice, suggesting its potential as a treatment for alopecia.

This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.

This animal study found that Laminaria japonica mixed with insulin-like growth factor-1 significantly promoted hair growth in mice, suggesting its potential use for treating alopecia pending further clinical trials.

This study found that adding 7% Ecklonia cava extract to oxidative hair dyes significantly reduced their cytotoxicity and oxidative stress without affecting color performance.

This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.

This study found that mesotherapy with placenta polypeptide injection significantly reduced skin inflammation and improved aesthetic outcomes in adults with moderate-to-severe sensitive skin, without increasing adverse events compared to controls.

This study found that human placenta hydrolysate reduced SARS-CoV-2 replication and improved immune response in ferret models, suggesting potential as a COVID-19 treatment.