22 citations
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May 2006 in “Experimental and Clinical Endocrinology & Diabetes” This study found that calculated parameters like free testosterone and bioavailable testosterone were higher in women with hirsutism and PCOS compared to controls, suggesting these might better assess hyperandrogenemia than measured hormone values.
December 1990 in “PubMed” This article discusses the role of androgens in causing hirsutism and male pattern baldness in women and emphasizes the need for antiandrogen treatment to manage these conditions, without reporting new clinical results.
166 citations
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March 2007 in “Hypertension” In this study, hyperandrogenemia in young women with polycystic ovary syndrome was linked to higher blood pressure, independent of factors like age, insulin resistance, obesity, or dyslipidemia.
99 citations
,
June 1999 in “The Journal of Clinical Endocrinology and Metabolism” This commentary discusses the potential use of testosterone therapy for various conditions in women and reports no new clinical results; the authors advocate for more discussion and research in this area.
8 citations
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March 2010 in “Gynecological Endocrinology” This study assessed various androgens' diagnostic effectiveness for hyperandrogenaemia in PCOS using ROC curve analysis, but it reports no specific new results.
April 2021 in “Journal of evolution of medical and dental sciences” This study found that bioavailable testosterone and the free androgen index were significantly associated with various clinical and biochemical features of PCOS, including hirsutism, showing higher levels in PCOS patients compared to controls.
28 citations
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February 2011 in “Clinical Endocrinology” In this study, women with polycystic ovary syndrome showed adverse lipoprotein profile changes that increase cardiovascular risk, which were found to be more closely related to androgen levels than body weight.
2 citations
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June 2022 in “Scientific reports” This study found that women with PCOS had significantly higher hair cortisol concentrations, suggesting hyperactivation of the HPA axis may affect metabolic and inflammatory markers in those with elevated cortisol levels.
September 2014 in “Springer eBooks” This review discusses how sex hormone levels and local steroid synthesis influence gender differences in aging skin, reporting no new clinical results.
51 citations
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November 1988 in “The Journal of Clinical Endocrinology & Metabolism” This study found that serum 3 alpha-Adiol-G levels in men are significantly associated with chest hair density and acne, indicating its role in reflecting androgen activity in peripheral tissues.
25 citations
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October 1993 in “American Journal of Physical Anthropology” This study observed that in Namibian/Southern African men, hormone levels, particularly estradiol, influence the growth of body hair, with different effects noted in various ethnic groups.
177 citations
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June 1991 in “The Journal of Clinical Endocrinology & Metabolism” This study found that caucasian subjects had higher serum levels of 5 alpha-reduced androgen metabolites compared to Chinese subjects, suggesting racial differences in 5 alpha-reductase activity and a potential mechanism for increased body hair in caucasian men.
30 citations
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January 2008 in “The Aging Male” This study found no difference in male pattern baldness between patients with benign prostate hyperplasia and prostate cancer, and no correlation with serum androgen levels.
January 2010 in “Yearbook of Endocrinology” Older men with lower levels of available testosterone are more likely to be frail.
255 citations
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October 1985 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
20 citations
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February 2017 in “International Journal of Dermatology” This review highlights recent findings on blood-derived autologous therapies for skin repair and wound healing but presents no new clinical results, emphasizing future challenges and prospects in regenerative dermatology.
29 citations
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December 2019 in “Transfusion and Apheresis Science” This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.
November 2024 in “Applied Sciences” This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.
4 citations
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December 2021 in “Pharmacological Reports” This study found that metformin's metabolic benefits, such as reducing fat content and improving insulin sensitivity, were less pronounced in men with early-onset androgenic alopecia compared to those with normal hair growth, possibly due to differences in systemic inflammation and vitamin D status.
1 citations
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November 2020 in “Cureus” This study found that severity of female pattern hair loss in premenopausal women was related to other clinical signs of hyperandrogenism like hirsutism and acne, but not to biochemical measures of hyperandrogenism.
9 citations
,
February 2005 in “The Journal of Men's Health & Gender” This article reviews treatment options for male androgenetic alopecia, including their distinct aims of arresting progression, stimulating regrowth, and concealing hair loss, and reports no new clinical results.
99 citations
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June 2005 in “Journal of Cosmetic Dermatology” This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
13 citations
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September 2020 in “Dermatologic Therapy” This review discusses the use of microneedling for androgenetic alopecia and finds it promising for enhancing hair density and thickness, especially when combined with other treatments, but notes no standardized protocol exists yet.
3 citations
,
August 2003 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This study documented that fiber hair implants effectively restored hair in over 85% of patients with permanent alopecia, with only mild and rare complications reported.
July 2026 in “Frontiers in Cellular and Infection Microbiology” This study found that patients with androgenetic alopecia had increased scalp microbial diversity and reduced Staphylococcus abundance, particularly in the frontal and vertex regions, suggesting this dysbiosis as a sensitive indicator of AGA.
January 2022 in “Indian journal of drugs in dermatology” This review of available data noted that oral minoxidil shows promise for treating various alopecia disorders, including androgenetic alopecia and alopecia areata, but high-quality studies are needed to better understand its effectiveness and mechanisms in these conditions.
September 2004 in “Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles)” This article reviews treatments for androgenic alopecia, discussing options like minoxidil for both genders and specific therapies for men and women, but it reports no new clinical results.
63 citations
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September 2020 in “Frontiers in Microbiology” This review discusses the potential health benefits of probiotics as a "Bio-Therapy" in food and medicine, noting that more research is needed to fully understand their mechanisms and effectiveness.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
53 citations
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March 2014 in “Cold Spring Harbor Perspectives in Medicine” The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.