November 2025 in “International Journal of Bio-resource and Stress Management” This review discusses MRSA in dogs and its public health impact, highlighting interspecies transmission and the need for improved infection control and biosecurity measures, but reports no new experimental results.
January 2019 in “Springer Reference Medizin” This article reviews the role of factor Xa inhibitors like Rivaroxaban and suggests they may eventually replace vitamin K antagonists, but their side effects require further clarification.
August 2012 in “Nature Cell Biology” In this study, researchers found that β-catenin directly promotes TERT expression in stem and cancer cells by interacting with the Tert promoter, illustrating a mechanistic link between tumorigenesis and pluripotency.
This case study reports that prolonged high-dose vitamin A intake led to multiple adverse health effects in a young man, which mostly resolved after stopping the supplement, although liver changes persisted.
April 1978 in “Pediatric research” This study found that zinc levels in hospitalized patients with significant weight loss did not correlate with taste perception or vitamin A status, even in those with reduced taste acuity.
December 2023 in “Medical Times” In this study, combining stromal cells and PRP resulted in a significantly higher cell count and volume than using a saline group, suggesting increased potential efficiency; however, clinical outcomes need further evaluation.
15 citations
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March 2023 in “Heliyon” This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.
15 citations
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July 2022 in “Frontiers in Pharmacology” This study suggests that Cepharanthine, a monomer in traditional Chinese medicine, may help treat COVID-19 by affecting multiple signaling pathways, and that TNF and IL-17 inhibitors used in rheumatoid arthritis, ankylosing spondylitis, and gouty arthritis might also be beneficial.
This study investigated the mechanisms of Platycladi Cacumen in treating androgenetic alopecia, identifying potential key components and targets but found no specific targets or regulatory mechanisms.
January 1992 in “Research Online (University of Wollongong)” This investigation reviews the potential impact of polyunsaturated fatty acids on thyroid hormone action and does not report new results, highlighting a need for further research on dietary treatment for hyperthyroidism.
147 citations
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September 2006 in “Developmental Cell” This study found that Smad7 perturbs hair follicle development while promoting sebaceous gland formation by antagonizing Wnt/β-catenin signaling in transgenic mice.
86 citations
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December 2002 in “Tissue Antigens” In this study, researchers found that the AIRE G961C variant is a significant risk factor for severe alopecia areata and early-onset cases, particularly in patients with alopecia universalis.
81 citations
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March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause specific hair and scalp issues.
50 citations
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May 2020 in “FEBS Letters” This review discusses techniques for analyzing the cell cycle, highlighting emerging tools for measuring cell cycle speed at single-cell resolution in live animals, and reports no new results.
33 citations
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September 2017 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes woolly hair and hair loss.
3 citations
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November 2024 in “Viruses” This study found that cepharanthine significantly inhibits EqHV-8 infection in vitro and improves lung tissue pathology in infected mice by reducing oxidative stress through specific signaling pathways, suggesting its potential as a treatment for equid herpesvirus type 8.
1 citations
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January 2024 in “Medicine” This study investigated the effects of Taohong Siwu Decoction on deep vein thrombosis, identifying 56 potential targets and highlighting beta-sitosterol, quercetin, and kaempferol as key active components that may regulate inflammation through the PI3K/Akt pathway, potentially slowing disease progression.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that Adapalene, Diosmin, and Azelastine have potential as multi-target drugs against Onchocerca volvulus and its endosymbiont, which might offer new therapeutic options for treating river blindness, but further research is needed to confirm their effectiveness.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study used molecular docking simulations to identify Adapalene, Diosmin, and Azelastine as promising drugs for repurposing against Onchocerciasis by targeting Onchocerca volvulus and its endosymbiont; further research is suggested to confirm their efficacy.
January 2026 in “In Silico Research in Biomedicine” This study used computational methods to explore the potential of betulinic acid from Ziziphus spina-christi in treating alopecia, suggesting its possible protective effects on hair follicles by enhancing genomic stability and reducing oxidative damage, meriting further experimental validation.
November 2023 in “Scientific reports” This study presents the first report on cloning and characterizing the full-length cDNA of SRD5A1 in Indian catfish (Clarias magur), revealing expression differences across reproductive phases and increased expression post-Ovatide administration in ovaries and testis.
June 2022 in “Organic communications” This study explores potential treatments for post COVID-19 complications using natural substances through molecular docking, but reports no new clinical results and existing treatments remain limited to prophylaxis and therapeutics.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a mutation in the CST6 gene linked to a rare syndrome with symptoms affecting hair and skin, revealing cystatin M/E's role in maintaining epidermal homeostasis and hair follicle development.
April 2025 in “Pharmacognosy Magazine” In this study, researchers found that Compound Baqian Danshen Liniment may improve vitiligo in mice by promoting melanocyte activity and reducing inflammation and oxidative stress.
This review summarizes the roles of PDGF and its receptors in cell development and wound healing, reporting no new research findings; the authors emphasize PDGF's diverse biological functions.
12 citations
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December 2022 in “Current Protein and Peptide Science” This review discusses the molecular mechanisms and clinical applications of thymosin β4, highlighting its potential benefits for inflammation, wound healing, tumor metastasis, and other medical conditions but reports no new experimental results.
This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.
This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.
176 citations
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January 2003 in “Journal of Investigative Dermatology” This review summarizes the roles of bone morphogenetic proteins in the development and regulation of normal and diseased skin, but it does not provide new clinical results.
62 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified 16 novel high sulfur KAP genes and two KAP pseudogenes on chromosome 21q23, showing expression in a specific region of the hair fiber cuticle.