1 citations
,
July 2015 in “AACE clinical case reports” This case report details a postmenopausal woman with hyperandrogenism due to both adrenal adenoma and ovarian hyperthecosis, highlighting the effectiveness of hormonal suppression and venous sampling for diagnosis.
1 citations
,
September 2012 in “Expert Review of Endocrinology & Metabolism” This review discusses the clinical implications of female androgen deficiency and evaluates treatment options, emphasizing the need for cautious use of replacement therapy in women with severe deficiency and matching symptoms.
1 citations
,
May 2011 in “Journal of Obstetrics and Gynaecology” Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.
1 citations
,
January 2011 in “International Journal of Trichology” Hair follicle stem cells have significant potential for treating various disorders.
May 2026 in “International Journal of Pharmaceutical Quality Assurance” This study reported that among 95 women with polycystic ovarian syndrome at a tertiary care hospital in India, menstrual irregularities were the most common issue, affecting 86.3% of participants, with many also experiencing hyperandrogenic symptoms, obesity, and infertility.
April 2026 in “BMJ Case Reports” This case study highlights the challenges of diagnosing hyperandrogenism in postmenopausal women, reporting a patient with androgenic alopecia and high testosterone due to a benign Leydig cell tumor in the ovary; surgery successfully normalized testosterone levels.
January 2026 in “Frontiers in Oncology” This case report highlights that in postmenopausal women with severe hyperandrogenism, thorough adrenal and pelvic evaluations, hormonal profiling, and permanent pathology are essential for accurate diagnosis and management of androgen-secreting tumors, such as AGCTs, to prevent misdiagnosis and ensure effective treatment.
January 2026 in “Brazilian Journal of Development” This case study reported on a 62-year-old woman with ovarian hyperthecosis, which caused symptoms like hirsutism and elevated testosterone; after bilateral oophorectomy, her symptoms improved, suggesting the importance of considering this rare condition in hyperandrogenism diagnosis for postmenopausal women.
November 2025 in “Journal of Rangpur Medical College” In this study from Bangladesh Medical University, researchers found strong correlations between symptoms such as oligomenorrhea and amenorrhea with bilateral polycystic ovarian morphology in women with PCOS, highlighting the link between clinical symptoms and ultrasound findings in predicting the severity of the condition.
October 2025 in “Journal of the Endocrine Society” In this case study, a 62-year-old woman with ovarian hyperthecosis experienced normalization of elevated testosterone levels and improvement in hirsutism and hair loss following bilateral salpingo-oophorectomy.
October 2025 in “Journal of the Endocrine Society” This case study reported that sudden hyperandrogenism in postmenopausal women may indicate hormonally active ovarian tumors such as Leydig cell tumors, which can be effectively treated with surgery.
October 2025 in “Journal of the Endocrine Society” In this case study, a 68-year-old woman with hyperandrogenism and presumed ovarian origin responded well to GnRH agonist therapy, normalizing testosterone levels and stabilizing blood pressure, suggesting its effectiveness as a non-surgical treatment option.
May 2025 in “International Journal of Biology Pharmacy and Allied Sciences” This case study reports that Ayurvedic treatment resulted in significant clinical improvement and reduced ovary size in a 28-year-old woman with PCOD over a 2.5-month period.
October 2024 in “Journal of the Endocrine Society” This case report details a postmenopausal woman whose hyperandrogenism was attributed to ovarian stromal hyperplasia, ultimately resolved with bilateral salpingo-oophorectomy.
October 2024 in “Journal of the Endocrine Society” In this case report, a 62-year-old woman with hyperandrogenism and polycythemia was diagnosed with a rare ovarian steroid cell tumor, highlighting the importance of considering such tumors in similar presentations; surgical removal led to symptom and lab normalization.
October 2024 in “Journal of the Endocrine Society” This clinical case study reports on a postmenopausal woman experiencing hair loss and virilization symptoms, which were ultimately attributed to rare ovarian tumors identified after a bilateral salpingo-oophorectomy, despite normal imaging results.
October 2024 in “Journal of the Endocrine Society” This study examined a case of postmenopausal virilization in a woman and found that despite normal imaging, bilateral salpingo-oophorectomy revealed rare ovarian Leydig cell and Brenner tumors as the source of hyperandrogenism, with symptoms resolving post-surgery.
October 2024 in “Journal of the Endocrine Society” In this case report, the authors describe the diagnosis and management of a rare case of hyperandrogenism in a postmenopausal woman, attributed to coexisting ovarian Leydig cell and Brenner tumors, with improvement in symptoms following bilateral salpingo-oophorectomy.
October 2024 in “Journal of the Endocrine Society” In this case report, a rare association between Cushing's syndrome caused by ectopic ACTH from cervical cancer is documented, highlighting the diagnostic challenges, treatment complexity, and high morbidity and mortality, with the patient succumbing to septic shock post-surgery.
October 2024 in “Journal of the Endocrine Society” In this case report, a 66-year-old postmenopausal woman with hyperandrogenism and alopecia underwent bilateral salpingo-oophorectomy, which revealed rare synchronous ovarian tumors causing virilization, highlighting the importance of surgical exploration despite normal imaging.
October 2024 in “Journal of the Endocrine Society” This case report highlighted a rare instance of Cushing's syndrome caused by ectopic ACTH from cervical cancer, demonstrating diagnostic challenges, treatment complexity, and high risks of morbidity and mortality, with less than 10 cases documented overall.
In this case report, a 54-year-old woman with hirsutism was found to have a benign ovarian cystadenofibroma, which resolved after surgery, highlighting the importance of evaluating postmenopausal women for ovarian causes of androgen excess.
November 2023 in “JCEM Case Reports” In this case report, a 55-year-old postmenopausal woman was diagnosed with ovarian hyperthecosis as the cause of her hyperandrogenism after detailed hormonal and imaging investigations, which was successfully treated with bilateral salpingo-oophorectomy, leading to symptom improvement and normalized testosterone levels.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
October 2023 in “Journal of the Endocrine Society” In this case report, a post-menopausal woman with symptoms such as hirsutism and elevated testosterone underwent surgery, which revealed hormonally active ovarian cellular fibromas, leading to symptom resolution and normalized hormone levels; the authors suggest further exploration of these tumors' hormonal effects.
October 2023 in “Journal of the Endocrine Society” This case report describes a rare instance of hyperandrogenism and increased hirsutism associated with endometrial cancer in a postmenopausal woman, with symptoms resolving and androgen levels normalizing after a total laparoscopic abdominal hysterectomy and bilateral oophorectomy.
October 2023 in “Journal of the Endocrine Society” This case report details a 73-year-old woman with significant hirsutism and hair loss linked to a rare ovarian Leydig cell tumor, which was resolved by bilateral salpingo-oophorectomy, normalizing her testosterone levels and addressing her symptoms.
July 2023 in “Journal of ayurveda and integrated medical sciences” This case report details the treatment of a 28-year-old woman with PCOS symptoms, including irregular menstruation, weight gain, and hair loss, using Ayurvedic management after ultrasound showed a bilateral PCO pattern.
July 2023 in “Endocrinology, diabetes & metabolism case reports” This case report involved a premenopausal woman with rapidly progressing virilizing symptoms caused by a rare sertoliform endometrioid carcinoma of the ovary. Following surgical intervention, her symptoms improved, highlighting the importance of recognizing virilizing symptoms as potential indicators of low-grade ovarian malignancies in similar cases.
June 2023 in “Scholars journal of medical case reports” This case report describes a 45-year-old Malian woman with Vogt-Koyanagi-Harada disease, highlighting its uncommon occurrence among individuals of African descent and detailing her treatment with prednisone and other adjunct therapies.