In this case report, a 59-year-old woman experienced burning sensations and developed atrophic, hypopigmented, ivory papules and plaques on her palms and soles over three years, which worsened after walking for extended periods.
October 2023 in “Journal of the Endocrine Society” This case report highlights the potential benefits of unilateral adrenalectomy in treating primary bilateral macronodular adrenal hyperplasia, noting a high rate of remission and low risk of recurrence.
March 2021 in “Research Square (Research Square)” This study found that stress is likely the main cause of symmetrical alopecia in Formosan macaques, with higher stress hormone levels observed in affected individuals.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare occurrence of giant bilateral adrenal myelolipomas in a 28-year-old female with CAH, emphasizing that large, hormonally active, or painful myelolipomas should be surgically removed.
This study found that bilateral orchiectomy allows most transgender women to stop anti-androgen medications, with 91.7% discontinuing them post-surgery and 25% reducing estrogen use.
April 2020 in “Journal of the Endocrine Society” This case report details a post-menopausal woman with hirsutism and virilization due to rare Leydig cell tumors in both ovaries, underscoring the challenge of detecting such tumors with standard imaging.
April 2020 in “Journal of the Endocrine Society” This case report highlights Leydig cell hyperplasia as a rare cause of increased testosterone and postmenopausal hirsutism, resolved after bilateral salpingo-oophorectomy in a 64-year-old woman.
A 70-year-old man with skin cancer on both sides of his forehead was treated with surgery and cryotherapy, highlighting the need for early detection and prevention.
January 2020 in “Journal of South Asian Federation of Obstetrics and Gynaecology” In this case study, laparoscopic bilateral salpingo-oophorectomy was associated with reduced androgen levels and partial reversal of male-pattern hair loss in a postmenopausal woman with ovarian hyperandrogenism.
4 citations
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January 1992 in “American Journal of Ophthalmology” 1 citations
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December 2024 in “Case Reports in Dermatology” In this case study, the researchers reported a rare incidence of bilateral hyperpigmented macules on a patient's lower legs, possibly due to cyclophosphamide, suggesting that this chemotherapy drug may directly stimulate hair follicles to cause skin discoloration.
August 2026 in “Frontiers in Pharmacology” In this case report, a 27-year-old woman experienced severe multisystem toxicity, including toxic encephalopathy, vision, and hearing loss, after ingesting selenium at occupationally high doses, suggesting such exposure can lead to previously unreported effects of vision and hearing impairment.
January 2026 in “JCEM Case Reports” This case report presents a rare instance of recurrent ACTH-independent Cushing’s syndrome due to PBMAH, coinciding with the development of a pheochromocytoma, highlighting the need for thorough reevaluation in similar recurring cases.
December 2024 in “Australasian Journal of Dermatology” In this report, a rare case of gynecomastia was observed in a 76-year-old man using 0.25% topical finasteride for hair loss, with breast tenderness resolving after stopping treatment but persistent enlargement.
This report describes a complex case of postmenopausal hyperandrogenism with virilization and concurrent rare ovarian tumors, highlighting the critical role of interdisciplinary collaboration in diagnosing and managing such challenging scenarios.
125 citations
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February 2007 in “Journal of the American Academy of Dermatology” This study found that adding topical eflornithine to laser hair removal significantly improved the reduction of unwanted facial hair in women over a 6-month period, compared to laser treatment alone.
44 citations
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October 2009 in “Journal of the American Academy of Dermatology” This study reported that 1% bexarotene gel was well tolerated and possibly effective for inducing partial hair regrowth in alopecia areata, but more rigorous trials are needed to confirm its efficacy.
16 citations
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September 2009 in “Schweizer Archiv für Tierheilkunde” This case report describes an 8-year-old Russian Blue cat with bilateral adrenal carcinomas secreting high levels of progesterone, showing symptoms similar to hypercortisolism.
7 citations
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January 2011 in “Veterinary Pathology” In this case report, a 9-year-old horse was diagnosed with alopecia areata contributing to Malassezia dermatitis, involving lymphocyte infiltration and symptoms consistent with yeast presence.
3 citations
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February 2019 in “Journal of endourology case reports” This report discusses a rare case of polypoid cystitis in a 45-year-old Asian man, which mimicked a bladder tumor and caused bilateral upper tract obstruction that was successfully treated through staged endoscopic management, ureteral stenting, and oral steroids.
2 citations
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August 2008 in “Oncotarget” In this study, intravital microscopy in live mice showed that apoptosis in hair follicle regression may be driven by apoptotic cells inducing neighboring cell death, with stem cells likely providing a pro-survival signal.
2 citations
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January 2003 in “Journal of Clinical Dermatology” This report documents the first cases in Korea of painful bilateral gynecomastia associated with taking 1mg of oral finasteride (Propecia) for male androgenetic alopecia.
1 citations
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April 2025 in “Romanian Journal of Ophthalmology” This study indicates that central serous chorioretinopathy linked to topical minoxidil use is rare, suggesting the need for early detection and discontinuation if it occurs.
July 2025 in “Dermatology Practical & Conceptual” A 2-year-old boy has a rare hair disorder causing brittle hair and hair loss, which may improve with age.
January 2025 in “Surgical & Cosmetic Dermatology” This article reviews temporal triangular alopecia, emphasizing the utility of dermoscopy for diagnosis, and reports no new clinical treatment findings.
July 2024 in “LA CIENCIA AL SERVICIO DE LA SALUD Y NUTRICIÓN” In this report, a newborn female with bilateral symmetrical alopecia lesions was diagnosed with congenital triangular alopecia, an unusual presentation, highlighting the disorder's benign nature and the importance of early recognition and conservative management.
April 2019 in “Journal of the Endocrine Society” This case report described a 62-year-old postmenopausal woman with hirsutism whose symptoms improved after a hysterectomy and bilateral oophorectomy, revealing bilateral ovarian hyperthecosis.
January 2013 in “Kidney international” This report describes a clinical case of a 38-year-old man diagnosed with Birt-Hogg-Dubé syndrome, confirmed by genetic testing, highlighting the presentation of multiple renal tumors and bilateral lung cysts.
80 citations
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March 2004 in “Neuropediatrics” This article presents an update on a family with Coats' plus disorder, documenting additional symptoms and two new similar cases, and reviews literature suggesting a link to dyskeratosis congenita for potential molecular insights.
21 citations
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July 2005 in “European Journal of Emergency Medicine” This case report discusses hair-tourniquet syndrome in infants, emphasizing the importance of early diagnosis and treatment to prevent serious complications.