December 2023 in “International Journal of Health and Pharmaceutical” This study investigated the effects of a derma pen treatment using green betel leaf extract cream on hair development in female Wistar rats, highlighting the antioxidant and anti-inflammatory properties of betel leaves that may aid in hair growth and condition.
July 2026 in “International Journal of Drug Delivery Technology” This study evaluated a Piper betle leaf emulgel for topical use and found it to have good stability, non-irritant properties, and significant hair growth activity in albino mice, suggesting its potential for dermatological and hair growth applications.
3 citations
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October 2018 in “International Journal of Green Pharmacy” This study suggested that an herbal shampoo containing Piper betle and Psidium guajava leaves extract may promote hair growth due to its antioxidant properties and showed stability for two months.
June 2022 in “International Journal for Research in Applied Science and Engineering Technology” The research developed a herbal shampoo using extracts from Piper Betel and Psidium Guajava leaves, which showed potential in promoting hair growth and managing hair diseases, while replacing synthetic ingredients with safe natural alternatives.
10 citations
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January 2022 in “Journal of Research in Pharmacy” In this experimental study on Wistar albino rats, Cotinus coggygria leaf extract demonstrated potential as a treatment for burn-induced skin damage by reducing cytokine levels and promoting tissue healing.
In this study, the combination of binahong leaf and lemongrass extracts was found to effectively inhibit the growth of the dandruff-causing fungus Pityrosporum ovale, with the strongest fungal growth inhibition observed at a 50% concentration of each extract.
44 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that Piper nigrum leaf extract showed in vivo anti-androgenic activity and potent 5α-reductase inhibitory effects, with piperine and (−)-cubebin identified as active components.
January 2022 in “JPK Jurnal Proteksi Kesehatan” This study found that the ethanol extract of mangkokan leaf (Polyscias scutellarium) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with higher concentrations showing greater inhibition zones, particularly against Staphylococcus aureus.
In this study, clove leaf ethanol extract shampoo at 15% concentration effectively promoted hair growth in male white rats, though it was less effective than 5% minoxidil.
7 citations
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August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
March 2024 in “International Research Journal of Modernization in Engineering Technology and Science” In this study, researchers developed a herbal shampoo using natural plant extracts, which maintained physicochemical properties and improved hair texture without the side effects commonly associated with synthetic ingredients.
October 2015 in “Elsevier eBooks” Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.
165 citations
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February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
19 citations
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April 2024 in “Journal of Umm Al-Qura University for Applied Sciences” This review explores the diverse roles of rosemary, covering its nutritional and medicinal uses, cosmetic and pharmaceutical applications, and evaluates various extraction methods, with a focus on sustainable practices and commercial prospects.
5 citations
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August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.
April 2024 in “The journal of phytopharmacology” This study found that extracts from orchid calluses can stimulate hair follicle growth and enhance the proliferation of hair follicle stem cells in vitro, suggesting potential applications in sustainable hair care products using natural bioactive compounds.
November 2024 in “International Journal of Biology Pharmacy and Allied Sciences” This study aimed to evaluate a herbal shampoo made from custard apple leaves for its physical properties, skin irritability, and foam formation, with a focus on efficacy and safety, particularly for addressing hair issues like lice infection.
October 2025 in “INSOLOGI Jurnal Sains dan Teknologi” In this laboratory study on rabbits, the researchers observed that both FET and FHE fractions improved hair length and weight, but minoxidil still led to better results, highlighting the comparative effects of different treatments on hair growth over 28 days.
November 2023 in “International Journal For Multidisciplinary Research” This review explores how herbal hair oils made from ingredients like amla and hibiscus may offer benefits such as reducing hair loss and dandruff, but these are summarized from existing research rather than new experimental data.
February 2024 in “International journal of biology, pharmacy and allied sciences” This review discusses the potential of plant-based preparations for treating hair loss and reports no new clinical results; the authors highlight herbs with evidence of efficacy against alopecia.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
6 citations
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March 2014 in “Herba Polonica” This article reviews treatment options for androgenetic alopecia, highlighting potential uses of plant materials, but reports no new clinical results.
June 2017 in “Journal of Traditional and Folk Practices” This study enumerates the traditional uses of Begonia malabarica by tribes in Tamil Nadu, where it is reported to be used for treating a variety of ailments, with further research planned to evaluate its biological potential.
3 citations
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January 2023 in “Journal of Hunan University Natural Sciences” In this study, researchers developed a natural shampoo using traditional plant extracts and reported that its physicochemical properties and antioxidant activity were comparable to marketed shampoos. Further research is needed to confirm its performance and quality.
34 citations
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August 2011 in “Journal of Natural Medicines” This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.
December 2025 in “Revista em Agronegócio e Meio Ambiente” This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.
October 2024 in “Current Trends in Biotechnology and Pharmacy” In this study, researchers developed a halal shampoo containing Centella asiatica and Phyllanthus emblica extracts, finding that a formula with specific concentrations exhibited high antioxidant activity and ideal physicochemical properties for hair cleansing and potential hair growth promotion.
2 citations
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August 2019 in “Journal of drug delivery and therapeutics” This study reports the formulation and evaluation of an herbal shampoo, "Herbello", aimed at improving antidandruff activity using various natural ingredients.
34 citations
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January 2022 in “Molecules/Molecules online/Molecules annual” This review highlights the use of natural products in cosmetic-containing herbals for skin and hair care but reports no new clinical results, calling attention to their claimed curative properties and minimal side effects.
4 citations
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April 2021 in “Majalah Farmasetika” This review discusses formulations and evaluation of herbal shampoos for hair growth stimulation, finding licorice extract shampoo to be the most effective, and reports no new clinical results.