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Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

CIP/KIP proteins help stop cell division and support hair growth.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

JAK inhibitors may soon be a safe and effective treatment for alopecia areata.

Mast cells might contribute to hair loss by causing skin thickening.

A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.

Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.

Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.

A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.

Testosterone reduces key molecules needed for early pregnancy in rats.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.