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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Probiotic bacteria improved skin and hair health in aged mice.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.