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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Activating TRPV3 stops human hair growth.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Minoxidil treats high blood pressure and side effects can be managed.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

The research found that a specific gene mutation causes fewer hair follicles and disrupted hair growth cycles, leading to thin and short hair in people with Hypotrichosis with Juvenile Macular Dystrophy.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

DA-9401 helps protect rat testis from finasteride damage.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

Dutasteride and finasteride affect different cell types differently.