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Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.

Polypoid cystitis can mimic bladder cancer but can be effectively treated with surgery, stents, and medication.

Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.

Surgical removal of a scalp keratoacanthoma is effective and prevents recurrence, but hair may not regrow.

Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.

Saw palmetto can help with prostate issues and may promote hair growth.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Certain drugs that block specific enzymes can help treat prostate diseases.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.