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New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Men with enlarged prostates often have more severe baldness.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

Finasteride improves urinary function in men for 2 years.

Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.

A 90-year-old man was diagnosed with heart failure due to wild-type transthyretin cardiac amyloidosis.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Lespedeza cuneata extract may help treat enlarged prostate.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Finasteride helps reduce heart enlargement in heart failure patients.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.