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    Research 211–240 of 1000+

    1. Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010 · 223 citations
    2. Effects of Finasteride (MK-906), a 5<i>α</i>-Reductase Inhibitor, on Circulating Androgens in Male Volunteers* The Journal of Clinical Endocrinology and Metabolism · 1990 · 147 citations
    3. A New Look at the 5?-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006 · 137 citations
    4. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    5. Structure of human type II 5 alpha-reductase gene. Endocrinology · 1992 · 124 citations
    6. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    7. Guideline for the primary care management of male lower urinary tract symptoms British Journal of Urology · 2004 · 97 citations
    8. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996 · 93 citations
    9. Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol Medicines · 2016 · 75 citations
    10. Comparison of Finasteride (Proscar®) and Serenoa repens (Permixon®) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers European Urology · 1994 · 73 citations
    11. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations
    12. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    13. Anti-androgenic activities of Ganoderma lucidum Journal of Ethnopharmacology · 2005 · 70 citations
    14. Combined Sabal and Urtica extract vs finasteride in BPH (Alken stage I–II) Der Urologe · 1997 · 69 citations
    15. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 65 citations
    16. Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum Food Chemistry · 2006 · 64 citations
    17. A model for the turnover of dihydrotestosterone in the presence of the irreversible 5α-reductase inhibitors GI198745 and finasteride Clinical Pharmacology & Therapeutics · 1998 · 60 citations
    18. Discovery and Clinical Development of Dutasteride, a Potent Dual 5&#945;- Reductase Inhibitor Current topics in medicinal chemistry · 2006 · 58 citations
    19. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials The Journal of Sexual Medicine · 2016 · 57 citations
    20. Pre-receptor regulation of the androgen receptor Molecular and cellular endocrinology · 2007 · 56 citations
    21. Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study Steroids · 1998 · 56 citations
    22. Edible seeds from Cucurbitaceae family as potential functional foods: Immense promises, few concerns Biomedicine & Pharmacotherapy · 2017 · 54 citations
    23. Significance of the polyglutamine tract polymorphism in the androgen receptor Urology · 2001 · 54 citations
    24. A Comparison of Varying alpha-Blockers and Other Pharmacotherapy Options for Lower Urinary Tract Symptoms. PubMed · 2005 · 52 citations
    25. Intraoperative floppy-iris syndrome and finasteride intake Journal of Cataract and Refractive Surgery · 2007 · 49 citations
    26. Selective non-steroidal inhibitors of 5α-reductase type 1 2004 · 49 citations
    27. Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5α-reductase II Advances in Therapy · 2010 · 46 citations
    28. Acute urinary retention: risks and management. PubMed · 2005 · 46 citations
    29. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations
    30. New 5?-reductase inhibitors: In vitro and in vivo effects Steroids · 2005 · 45 citations