research Long-Term Treatment with Finasteride Induces Apoptosis and Pathological Changes in Female Mice
Finasteride causes harmful organ changes in female mice.
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research Five-Alpha Reductase Inhibitor and Breast Cancer Risk in Men: A Systematic Review
Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
research The Influence of Low Dose Finasteride, a Type II 5α-Reductase Inhibitor, on Circulating Neuroactive Steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Finasteride Induced Hyperglycemia
Finasteride may worsen blood sugar control in diabetic patients.
research Adverse Effects of 5-Alpha Reductase Inhibitor Therapy in Men With Androgenetic Alopecia: Is There Cause for Concern?
5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
research The Impact of Potential Pill Splitting on Generic and Branded Finasteride Uptake
Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.
research A 57-Year-Old Male Retired Colonel with Acute Ankle Swelling
The retired colonel's ankle swelling was caused by a reaction to the antibiotic levofloxacin.
research Analytical Methods of Dutasteride: An Overview
Dutasteride is more effective than finasteride for hair loss treatment.
research Finasteride Effectively Attenuates the Impairments of Left Ventricular Function and Cardiac Sympathovagal Balance in Both Aging and Obese Male Rats via Reducing Systemic Oxidative Stress
Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
research Cost Comparison of Patients with Chronic Hand Eczema Covered by Statutory vs. Occupational Health Insurances in Germany
Treating chronic hand eczema costs about the same in statutory and occupational health insurances in Germany, but work-related cases may lead to higher indirect costs due to longer work absences.
research Cataract Surgery Guidelines in Europe: A Literature Review and Document Search in 15 Countries
Cataract surgery guidelines vary across Europe, and generic finasteride sales for hair loss have grown due to pill splitting.
research Economic Analysis of Cataract Surgery in Europe: An Analysis of Hospital Databases Available in 11 Countries
Cataract surgery in Europe varies in frequency and cost between countries.
research Use of Call Center Methodology to Collect Quality of Life Data in a Clinical Trial: A Case Study of Patients with Diabetic Macular Edema
Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.
research Does PSADT After Radical Prostatectomy Predict Overall Survival?—A Report from the SEARCH Database Group
Shorter PSADT after prostate surgery is linked to higher risk of death.
research Urological Oncology: Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors and has side effects; biopsy methods have similar outcomes; psychosocial factors affect sexual recovery post-surgery.
research Finasteride: Suicidality or Psychological Adverse Events
Finasteride use linked to increased suicidality in patients under 45.
research Epigallocatechin Gallate and Tannic Acid Based Formulations of Finasteride for Dermal Administration and Chemoembolization
Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
research Finasteride and Sperm Concentration: Rapid Systematic Review
Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
research Depression and Suicidal Thoughts with Finasteride (Propecia)
Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
research Health Canada: No Link Between Finasteride Use and Seizures
No link between finasteride and seizures found.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation
Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia
Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
research Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss
Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.