research Aldo-Keto Reductase (AKR) 1C3 Inhibitors: A Patent Review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
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research Uric Acid in a Male's Life
High uric acid can cause health issues, so managing it with lifestyle changes is important.
research Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Hair Loss: A Harbinger of Morbidities to Come
Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
research Oral Bicalutamide for Female Pattern Hair Loss: A Pilot Study
Bicalutamide improves hair density in women safely.
research Analytical Methods of Dutasteride: An Overview
Dutasteride is more effective than finasteride for hair loss treatment.
research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia
Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
research A Double-Blind, Randomized, Placebo-Controlled Pilot Study to Investigate the Effects of Finasteride Combined with a Biodegradable Self-Reinforced Poly L-Lactic Acid Spiral Stent in Patients with Urinary Retention Caused by Bladder Outlet Obstruction
Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.
research Anti-Nociceptive and Anti-Inflammatory Properties of 5alpha-Reductase Inhibitor Finasteride in Experimental Animals
Finasteride helps reduce pain and inflammation in animals.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Safety Profile of Finasteride: Distribution of Adverse Effects According to Structural and Informational Dichotomies of the Mind/Brain
Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
research Five-Alpha Reductase Inhibitor and Breast Cancer Risk in Men: A Systematic Review
Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
research Stability Indicating Method Development and Validation of Finasteride by High-Performance Thin-Layer Chromatography Studies
New method effectively analyzes finasteride and its stability.
research Optimized Nanostructured Lipid Carriers for Dutasteride Delivery: Improving Therapeutic Efficiency and Minimizing Adverse Effects
The new delivery method for dutasteride is more effective and has fewer side effects.
research Relationship Between Lower Urinary Tract Symptoms and Prostatic Anatomical Characteristics in Patients With Obesity and Severe Obesity
Obesity is linked to more severe lower urinary tract symptoms.
research Choice of Recall Period for Patient-Reported Outcome Measures: Criteria for Consideration
Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.
research Finasteride in the Treatment of Androgenetic Alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride
Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
research Anti-Androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium Japonicum): Active Constituents Inhibiting Testosterone 5α-Reductase
Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.
research Synthesis and Pharmacological Evaluation of New 16-Methyl Pregnane Derivatives
New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
research Post-Finasteride Syndrome
Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.
research Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors
Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.
research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model
Oral finasteride and dutasteride may negatively affect erectile function in rats.
research Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Epigallocatechin Gallate and Tannic Acid Based Formulations of Finasteride for Dermal Administration and Chemoembolization
Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia
Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research Androgen Sensitivity Gateway to COVID-19 Disease Severity
Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.
research Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.